Health effects of omega-3 polyunsaturated fatty acids in common diseases


Citation

Jia G., . and Qiong Z., . and Yong-Hua W., . Health effects of omega-3 polyunsaturated fatty acids in common diseases. pp. 1098-1108. ISSN 22317546

Abstract

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) such as alpha-linolenic eicosapentaenoic and docosahexaenoic acids mostly exist in marine-derived foods and have shown beneficial effects for hypertriglyceridemia endothelial function inflammation and oxidative stress. Studies suggest that n-3 PUFAs can regulate the activity of NF-B Nrf2 SREBP-1c and PPAR which are linked to inflammations ROS homeostasis and lipid metabolism. Several epidemiological trials and physiological studies indicated protective effect of n-3 PUFAs against various common diseases such as cardiovascular diseases diabetes mellitus and non-alcoholic fatty liver disease. This review summarises the findings of many such studies highlighting the beneficial effects of n-3 PUFAs.


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Abstract

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) such as alpha-linolenic eicosapentaenoic and docosahexaenoic acids mostly exist in marine-derived foods and have shown beneficial effects for hypertriglyceridemia endothelial function inflammation and oxidative stress. Studies suggest that n-3 PUFAs can regulate the activity of NF-B Nrf2 SREBP-1c and PPAR which are linked to inflammations ROS homeostasis and lipid metabolism. Several epidemiological trials and physiological studies indicated protective effect of n-3 PUFAs against various common diseases such as cardiovascular diseases diabetes mellitus and non-alcoholic fatty liver disease. This review summarises the findings of many such studies highlighting the beneficial effects of n-3 PUFAs.

Additional Metadata

[error in script]
Item Type: Article
AGROVOC Term: Nutritional supplements
AGROVOC Term: Polyunsaturated fatty acids
AGROVOC Term: Hyperlipidaemia
AGROVOC Term: Metabolic disorders
AGROVOC Term: Inflammation
AGROVOC Term: analysis
AGROVOC Term: Oxidative stress
AGROVOC Term: Cardiovascular diseases
AGROVOC Term: Diabetes mellitus
AGROVOC Term: Hypertriglyceridemia
Depositing User: Mr. AFANDI ABDUL MALEK
Last Modified: 24 Apr 2025 00:55
URI: http://webagris.upm.edu.my/id/eprint/10064

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