Synthesis characterisation and density functional theory study of encapsulated bioactive components of ginger

Yusfi Meqorry, . and Adhika Damar Rastri, . and Aksono Eduardus Bimo, . and Sarassina Raden Roro Fosa, . and Wungu Triati Dewi Kencana, . and Wijaya Christofora Hanny, . and Anindya Atsarina Larasati, . and Suprijadi, . Synthesis characterisation and density functional theory study of encapsulated bioactive components of ginger. pp. 2645-2657. ISSN 2231-8526

In this paper we encapsulated ginger bioactive components in maltodextrin nanocapsules. Ginger nanocapsules were characterised using Transmission Electron Microscope (TEM) and Particle Size Analyser (PSA). The results show that the nanoparticles have a generally globular shape with particle size under 200 nm. In addition the simulation of gingerol and dextran as a representative for maltodextrin was also investigated using Density Functional Theory (DFT) calculation. From the DFT calculation gingerol exhibited a physisorption interaction with dextran by forming hydrogen bonds. Furthermore the density of state analysis shows that the gingeroldextran system has a conductive-like behaviour that promotes the nanocapsules cell uptake.

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Abstract

In this paper we encapsulated ginger bioactive components in maltodextrin nanocapsules. Ginger nanocapsules were characterised using Transmission Electron Microscope (TEM) and Particle Size Analyser (PSA). The results show that the nanoparticles have a generally globular shape with particle size under 200 nm. In addition the simulation of gingerol and dextran as a representative for maltodextrin was also investigated using Density Functional Theory (DFT) calculation. From the DFT calculation gingerol exhibited a physisorption interaction with dextran by forming hydrogen bonds. Furthermore the density of state analysis shows that the gingeroldextran system has a conductive-like behaviour that promotes the nanocapsules cell uptake.

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Item Type:	Article
AGROVOC Term:	Ginger
AGROVOC Term:	Encapsulation
AGROVOC Term:	analysis
AGROVOC Term:	Bioavailability
AGROVOC Term:	Computational biology
Depositing User:	Mr. AFANDI ABDUL MALEK
Last Modified:	24 Apr 2025 00:55
URI:	http://webagris.upm.edu.my/id/eprint/10136

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