Citation
Muhammad Ezzudin R., . and Rohini J., . and Rabeta M. S., . An attempt to improve the solubility and stability of Ocimum tenuiflorum aqueous leaves extract. pp. 357-365. ISSN 2550-2166
Abstract
Medicinal plants have gained attention in recent years due to the presence of various bioactive compounds which promote distinct health benefits and is less toxic. However the plants face common and serious problems due to their active compounds which are the solubility and stability. Ocimum tenuiflorum one of the ancient medicinal plants were its medicinal values have been widely studies. Yet study to improve its quality still lacking. Thus an effort was taken to study and improve the solubility and stability of the plant. Solid dispersions were prepared with extract and different types of surfactants at different ratio have used to improve the stability. Lecithin (1:1 ratio) have improved the solubility significantly (p0.05) when compared to extract. Enhancement in solubility hence improved the stability when stored at 4C of the solid dispersion of extract. Overall the study has successfully improved the quality of the extract with lecithin complex whereby the solubility and increases stability.
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Abstract
Medicinal plants have gained attention in recent years due to the presence of various bioactive compounds which promote distinct health benefits and is less toxic. However the plants face common and serious problems due to their active compounds which are the solubility and stability. Ocimum tenuiflorum one of the ancient medicinal plants were its medicinal values have been widely studies. Yet study to improve its quality still lacking. Thus an effort was taken to study and improve the solubility and stability of the plant. Solid dispersions were prepared with extract and different types of surfactants at different ratio have used to improve the stability. Lecithin (1:1 ratio) have improved the solubility significantly (p0.05) when compared to extract. Enhancement in solubility hence improved the stability when stored at 4C of the solid dispersion of extract. Overall the study has successfully improved the quality of the extract with lecithin complex whereby the solubility and increases stability.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Ocimum |
| AGROVOC Term: | Lamiaceae |
| AGROVOC Term: | Medicinal plants |
| AGROVOC Term: | Leaf extracts |
| AGROVOC Term: | Dispersions |
| AGROVOC Term: | HPLC |
| AGROVOC Term: | High performance liquid chromatography |
| AGROVOC Term: | Mass spectrometry |
| AGROVOC Term: | Solubility |
| AGROVOC Term: | Convergent improvement |
| Depositing User: | Mr. AFANDI ABDUL MALEK |
| Last Modified: | 24 Apr 2025 00:55 |
| URI: | http://webagris.upm.edu.my/id/eprint/10227 |
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