Acute oral toxicity study of wound healing drink from Ocimum tenuiflorum on adult female Sprague-Dawley rats


Citation

Rohini J., . and Rabeta M. S., . and Wan Ezumi M. F., . Acute oral toxicity study of wound healing drink from Ocimum tenuiflorum on adult female Sprague-Dawley rats. pp. 390-393. ISSN 2550-2166

Abstract

In this study the extract of Ocimum tenuiflorum was formulated to promote wound healing and no acute toxicity study has been reported on this type of formulation. Acute oral toxicity results of the rats after administration of 5000 mg/kg body weight (BW) formulation showed no toxic effects and behavioural changes of the rats after 14 days of observation. On day 14 the rats were anaesthetized to collect the vital organs for histopathological examination. The microscopy study of the visceral organs of wound healing powder group shows no sign of toxicity in comparison to untreated rats organs. In conclusion the result of the acute oral toxicity test of wound healing drink showed no sign of toxicity as corroborated by a histopathological study.


Download File

Full text available from:

Abstract

In this study the extract of Ocimum tenuiflorum was formulated to promote wound healing and no acute toxicity study has been reported on this type of formulation. Acute oral toxicity results of the rats after administration of 5000 mg/kg body weight (BW) formulation showed no toxic effects and behavioural changes of the rats after 14 days of observation. On day 14 the rats were anaesthetized to collect the vital organs for histopathological examination. The microscopy study of the visceral organs of wound healing powder group shows no sign of toxicity in comparison to untreated rats organs. In conclusion the result of the acute oral toxicity test of wound healing drink showed no sign of toxicity as corroborated by a histopathological study.

Additional Metadata

[error in script]
Item Type: Article
AGROVOC Term: Ocimum
AGROVOC Term: Lamiaceae
AGROVOC Term: Plant extracts
AGROVOC Term: Drinks
AGROVOC Term: Acute toxicity
AGROVOC Term: Rats
AGROVOC Term: Experimental animals
AGROVOC Term: Behaviour
AGROVOC Term: Histopathology
AGROVOC Term: Dietary value
Depositing User: Mr. AFANDI ABDUL MALEK
Last Modified: 24 Apr 2025 00:55
URI: http://webagris.upm.edu.my/id/eprint/10231

Actions (login required)

View Item View Item
Agris UPM is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.