Citation
Ida Farah Ahmad, . and Nur Salsabeela Mohd Rahim, . and Yew Terence Chin Tan, . Potential of Syzygium polyanthum (daun salam) in lowering blood glucose level: a review. pp. 2261-2277. ISSN 2231-8526
Abstract
Syzygium polyanthum is a herb widely used in Malaysia and Indonesia in cuisines. Traditionally the herbal decoction of S. polyanthum (daun salam) leaves is often used by diabetic patients in Indonesia. Therefore our objective is to evaluate the scientific evidence available for S. polyanthum in lowering blood glucose levels (BGL). We systematically searched Pubmed Google Scholar Scopus CENTRAL. LILAC and clinicaltrials.gov databases up to 23 October 2020 using the keywords Syzygium polyanthum� and antidiabetic�. From the selected 413 articles eight studies involving rodents were included. All results showed a significant effect in lowering BGL without any adverse effects. The possible underlying mechanism of action is attributed to inhibiting intestinal glucose absorption and enhancing glucose uptake by the muscles. Chemical families responsible for the effect were determined as flavonoids alkaloids and terpenoids. Thus S. polyanthum leaves showed potential antidiabetic properties but further research is required to identify the active compounds followed by the safety evaluation of this compound.
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Abstract
Syzygium polyanthum is a herb widely used in Malaysia and Indonesia in cuisines. Traditionally the herbal decoction of S. polyanthum (daun salam) leaves is often used by diabetic patients in Indonesia. Therefore our objective is to evaluate the scientific evidence available for S. polyanthum in lowering blood glucose levels (BGL). We systematically searched Pubmed Google Scholar Scopus CENTRAL. LILAC and clinicaltrials.gov databases up to 23 October 2020 using the keywords Syzygium polyanthum� and antidiabetic�. From the selected 413 articles eight studies involving rodents were included. All results showed a significant effect in lowering BGL without any adverse effects. The possible underlying mechanism of action is attributed to inhibiting intestinal glucose absorption and enhancing glucose uptake by the muscles. Chemical families responsible for the effect were determined as flavonoids alkaloids and terpenoids. Thus S. polyanthum leaves showed potential antidiabetic properties but further research is required to identify the active compounds followed by the safety evaluation of this compound.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Syzygium |
| AGROVOC Term: | Leaf extracts |
| AGROVOC Term: | Phytochemistry |
| AGROVOC Term: | Flavonoids |
| AGROVOC Term: | Terpenoids |
| AGROVOC Term: | Alkaloids |
| AGROVOC Term: | Diabetes mellitus |
| AGROVOC Term: | Blood glucose |
| AGROVOC Term: | Disease treatment |
| AGROVOC Term: | Disease control methods |
| Depositing User: | Mr. AFANDI ABDUL MALEK |
| Last Modified: | 24 Apr 2025 00:55 |
| URI: | http://webagris.upm.edu.my/id/eprint/10244 |
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