Citation
Mpopo M. S., . and Pillai M. K., . and Mekbib S. B., . 2 2-Diphenyl-1-picrylhydrazil radical scavenging activity of extracts from roots and leaves of Searsia burchellii. pp. 235-239. ISSN 2550-2166
Abstract
Searsia burchellii finds therapeutic applications in traditional medicine. Methanolic extracts hexane chloroform ethyl acetate and methanol/water fractions of methanolic extracts and water extracts were obtained separately from the roots and leaves of Searsia burchellii by the combination of maceration hot solvent extraction and solvent-solvent partition techniques. These extracts were evaluated for their antioxidant activity using 2 2- diphenyl-1-picrylhydrazil radical scavenging assay (DPPH). The extracts from roots and their fractions showed radical scavenging activity ranging from 6.604.50 to 63.271.93 at various concentrations. Similarly the extracts from leaves and their fractions showed radical scavenging activity ranging from 3.320.95 to 64.910.15 at various concentrations. Ascorbic acid served as positive control which showed radical scavenging activity ranging from 53.622.80 to 60.820.62 at various concentrations. The IC‚‚ values of these extracts and fractions were found to be 200 to 3000 g/mL. The IC‚‚ value of ascorbic acid was found to be 200 g/mL. From this study we concluded that extracts and their fractions from S. burchellii showed promising radical scavenging activity.
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Abstract
Searsia burchellii finds therapeutic applications in traditional medicine. Methanolic extracts hexane chloroform ethyl acetate and methanol/water fractions of methanolic extracts and water extracts were obtained separately from the roots and leaves of Searsia burchellii by the combination of maceration hot solvent extraction and solvent-solvent partition techniques. These extracts were evaluated for their antioxidant activity using 2 2- diphenyl-1-picrylhydrazil radical scavenging assay (DPPH). The extracts from roots and their fractions showed radical scavenging activity ranging from 6.604.50 to 63.271.93 at various concentrations. Similarly the extracts from leaves and their fractions showed radical scavenging activity ranging from 3.320.95 to 64.910.15 at various concentrations. Ascorbic acid served as positive control which showed radical scavenging activity ranging from 53.622.80 to 60.820.62 at various concentrations. The IC‚‚ values of these extracts and fractions were found to be 200 to 3000 g/mL. The IC‚‚ value of ascorbic acid was found to be 200 g/mL. From this study we concluded that extracts and their fractions from S. burchellii showed promising radical scavenging activity.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Anacardiaceae |
| AGROVOC Term: | Rhus |
| AGROVOC Term: | Leaf extracts |
| AGROVOC Term: | Root extracts |
| AGROVOC Term: | Evergreen plants |
| AGROVOC Term: | Shrubs |
| AGROVOC Term: | Diphenyl |
| AGROVOC Term: | Therapeutic substances |
| AGROVOC Term: | Free radicals |
| AGROVOC Term: | Traditional medicines |
| Depositing User: | Mr. AFANDI ABDUL MALEK |
| Last Modified: | 24 Apr 2025 00:55 |
| URI: | http://webagris.upm.edu.my/id/eprint/10408 |
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