Dietary exposure assessment of tetracycline residues in chicken meat on children and adults in peninsular Malaysia

Chai L. C., . and Syariena A., . and Ungku Fatimah U. Z. A., . and Marni S., . and Mahyudin N. A., . and Khairunnisak M., . and Marzura M. R., . Dietary exposure assessment of tetracycline residues in chicken meat on children and adults in peninsular Malaysia. pp. 1-10. ISSN 2180-3897

An exposure assessment was conducted to quantitate tetracyclines (TCs) in chickens and the risk estimates were calculated using deterministic and probabilistic approaches. The results revealed that through deterministic approach estimated daily exposure to TCs resulted in children aged 1y3 and 4y6 (0.05919 and 0.03946 g/kg bw/day) followed by adults (0.02847 g/kg bw/day) and children aged 7y10 at 0.02631 g/kg bw/day. Based on the probabilistic approach dietary exposure of Malaysian adults to TCs was estimated to range from 0.00174“0.35209 g/kg bw/day. In comparison for the children group the estimated exposure was higher in age 1y3 at 0.0137 “ 1.9845 g/kg bw/day followed by children aged 4y6 and 7y10 at 0.00718 “ 1.3967 g/kg bw/day and 0.00834 “ 0.91841 g/kg bw/day respectively. However the estimated risk calculated for all groups was 10 ADI. These indicate that toxicological risk with regard to the consumption of chicken meat could not be considered as a public health problem but the result can be supportive for the safety authorities to engage policies in managing any potential risk. The occurrence of high concentration of TCs residues in small samples still warrants closer monitoring and management of the use of TCs in chicken farms in Peninsular Malaysia.

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Abstract

An exposure assessment was conducted to quantitate tetracyclines (TCs) in chickens and the risk estimates were calculated using deterministic and probabilistic approaches. The results revealed that through deterministic approach estimated daily exposure to TCs resulted in children aged 1y3 and 4y6 (0.05919 and 0.03946 g/kg bw/day) followed by adults (0.02847 g/kg bw/day) and children aged 7y10 at 0.02631 g/kg bw/day. Based on the probabilistic approach dietary exposure of Malaysian adults to TCs was estimated to range from 0.00174“0.35209 g/kg bw/day. In comparison for the children group the estimated exposure was higher in age 1y3 at 0.0137 “ 1.9845 g/kg bw/day followed by children aged 4y6 and 7y10 at 0.00718 “ 1.3967 g/kg bw/day and 0.00834 “ 0.91841 g/kg bw/day respectively. However the estimated risk calculated for all groups was 10 ADI. These indicate that toxicological risk with regard to the consumption of chicken meat could not be considered as a public health problem but the result can be supportive for the safety authorities to engage policies in managing any potential risk. The occurrence of high concentration of TCs residues in small samples still warrants closer monitoring and management of the use of TCs in chicken farms in Peninsular Malaysia.

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Item Type:	Article
AGROVOC Term:	Chicken meat
AGROVOC Term:	Adults
AGROVOC Term:	Children
AGROVOC Term:	Tetracyclines
AGROVOC Term:	Residues
AGROVOC Term:	Diet treatment
AGROVOC Term:	Health risks
AGROVOC Term:	Farm management
AGROVOC Term:	Public health
Depositing User:	Mr. AFANDI ABDUL MALEK
Last Modified:	24 Apr 2025 01:15
URI:	http://webagris.upm.edu.my/id/eprint/10501

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