Biological functions of nutraceutical xylan oligosaccharides as a natural solution for modulation of obesity diabetes and related diseases

Teng C., . and Zhang C., . and Li X., . and Abdo A. A. A., . and Patil P., . and Liang X, . Biological functions of nutraceutical xylan oligosaccharides as a natural solution for modulation of obesity diabetes and related diseases. pp. 236-247. ISSN 22317546

Natural compounds have been used to regulate numerous metabolic dysfunctions such as obesity diabetes and dyslipidaemia. Xylan oligosaccharides (XOS) alleviate obesity diabetes and dyslipidaemia via the regulation of glucose and lipid metabolisms and the modification of gut microbiota. Moreover XOS is also shown to inhibit obesity diabetes and related metabolic disorders such as inflammation and oxidative stress by regulating the related genes and enzymes that contribute to the respective disorders. The information currently available does not offer in-depth elucidation regarding the molecular mechanisms of action of XOS in controlling obesity diabetes and related metabolic disorders thus remain to be elucidated. The present review discusses XOS and its mechanisms of action and key roles in regulating obesity diabetes and related metabolic disorders highlighting the potential use of this compound in the improvement of novel therapeutic approaches for the treatment of the aforementioned diseases.

Full text available from: Official URL: http://www.ifrj.upm.edu.my/29%20(02)%202022/02%20-...

Abstract

Natural compounds have been used to regulate numerous metabolic dysfunctions such as obesity diabetes and dyslipidaemia. Xylan oligosaccharides (XOS) alleviate obesity diabetes and dyslipidaemia via the regulation of glucose and lipid metabolisms and the modification of gut microbiota. Moreover XOS is also shown to inhibit obesity diabetes and related metabolic disorders such as inflammation and oxidative stress by regulating the related genes and enzymes that contribute to the respective disorders. The information currently available does not offer in-depth elucidation regarding the molecular mechanisms of action of XOS in controlling obesity diabetes and related metabolic disorders thus remain to be elucidated. The present review discusses XOS and its mechanisms of action and key roles in regulating obesity diabetes and related metabolic disorders highlighting the potential use of this compound in the improvement of novel therapeutic approaches for the treatment of the aforementioned diseases.

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Item Type:	Article
AGROVOC Term:	Xylans
AGROVOC Term:	Lignocellulose
AGROVOC Term:	Natural antioxidants
AGROVOC Term:	Biological properties
AGROVOC Term:	Obesity
AGROVOC Term:	Diabetes
AGROVOC Term:	Disease treatment
AGROVOC Term:	Disease control methods
Depositing User:	Mr. AFANDI ABDUL MALEK
Last Modified:	24 Apr 2025 00:55
URI:	http://webagris.upm.edu.my/id/eprint/10632

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