A new approach to the standardisation of medicinal plants

Hylands Peter J., . (2000) A new approach to the standardisation of medicinal plants. [Proceedings Paper]

The standardisation of medicinal plants has never been more important. Misidentification and adulteration have led to and are continuing to cause serious toxic side effects. Yet at the same time more and more evidence is validating the usefulness of plant medicines including the substantiation of synergism where the clinical effect is more efficacious less toxic or both than the isolated ingredients. This is reflected in a huge increase in the consumption of plant materials worldwide. The value of these materials is well demonstrated by the increasing incorporation of traditional Chinese medicines into the reimbursable health care systems of a number of Asian countries. Existing attempts at standardisation have been largely confined to reductionist approaches based on the identification and quantification of selected active ingredients and perhaps a single mechanism of action. Yet these approaches belie the observed value of synergism and are applicable only for those materials that have been very well studied in the laboratory. The presentation will present on alternative approach that allows highly precise standardisation both chemically and biologically without reliance on single active ingredients or mechanisms of action. Moreover the approach can also find application in the quality control of mixtures of plant extracts such as those used in traditional Chinese medicine.

Full text available from:

Abstract

The standardisation of medicinal plants has never been more important. Misidentification and adulteration have led to and are continuing to cause serious toxic side effects. Yet at the same time more and more evidence is validating the usefulness of plant medicines including the substantiation of synergism where the clinical effect is more efficacious less toxic or both than the isolated ingredients. This is reflected in a huge increase in the consumption of plant materials worldwide. The value of these materials is well demonstrated by the increasing incorporation of traditional Chinese medicines into the reimbursable health care systems of a number of Asian countries. Existing attempts at standardisation have been largely confined to reductionist approaches based on the identification and quantification of selected active ingredients and perhaps a single mechanism of action. Yet these approaches belie the observed value of synergism and are applicable only for those materials that have been very well studied in the laboratory. The presentation will present on alternative approach that allows highly precise standardisation both chemically and biologically without reliance on single active ingredients or mechanisms of action. Moreover the approach can also find application in the quality control of mixtures of plant extracts such as those used in traditional Chinese medicine.

[error in script]

Item Type:	Proceedings Paper
Additional Information:	Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal QK99 A1S471 2000 Call Number.
AGROVOC Term:	STANDARDS
AGROVOC Term:	DRUG PLANTS
AGROVOC Term:	TRADITIONAL MEDICINES
AGROVOC Term:	ALTERNATIVE METHODS
AGROVOC Term:	MALAYSIA
Geographical Term:	MALAYSIA
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 05:13
URI:	http://webagris.upm.edu.my/id/eprint/11272

Actions (login required)

View Item