Citation
Abdul Rashih A., . and Ong B. K., . and Mohd Radzi A., . and Mohd Ilham Adenan, . (2000) Inhibitory effects of Malaysian ulam on reverse transcriptase activity. [Proceedings Paper]
Abstract
The retrovirus family is characterised by the presence of reverse transcriptase enzyme in the virion. It is an essential enzyme required for the unique retroviral type of multiplication. A total of 30 aqueous extracts from 26 species of herbs consumed as ulam were evaluated for their inhibitory effect on the polymerase activity of reverse transcriptase. The leaf extracts of Diplazium esculentum and Pluchea indica at a concentration of 500 J.lg/ml showed strong inhibitory effect on the reverse transcriptase activity with percentage inhibition of more than 95. The ICso values obtained for D. esculentum and P. indica were 54.06 J.lg/ml and 92.91 J.lg/ml respectively.
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Abstract
The retrovirus family is characterised by the presence of reverse transcriptase enzyme in the virion. It is an essential enzyme required for the unique retroviral type of multiplication. A total of 30 aqueous extracts from 26 species of herbs consumed as ulam were evaluated for their inhibitory effect on the polymerase activity of reverse transcriptase. The leaf extracts of Diplazium esculentum and Pluchea indica at a concentration of 500 J.lg/ml showed strong inhibitory effect on the reverse transcriptase activity with percentage inhibition of more than 95. The ICso values obtained for D. esculentum and P. indica were 54.06 J.lg/ml and 92.91 J.lg/ml respectively.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal QK99 A1S471 2000 Call Number. |
| AGROVOC Term: | REVERSE TRANSCRIPTASE |
| AGROVOC Term: | ENZYME INHIBITORS |
| AGROVOC Term: | ENZYMES |
| AGROVOC Term: | HERBACEOUS PLANTS |
| AGROVOC Term: | MALAYSIA |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:14 |
| URI: | http://webagris.upm.edu.my/id/eprint/11316 |
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