Citation
Saiful Azmi J. Forest Research Institute Malaysia, . and Adiana M A., . (2009) Synthesis and anti-multidrug resistant Staphylococcuc aureus MRSA activity of alkylated apigenin. [Proceedings Paper]
Abstract
In the present study a derivative of apigenin namely 4-ethoxy-5 7 dimethoxyflavone has been synthesized from phioroacetophenone via its chalcone precursor followed by the treatment of iodine in dimethylsulfoxide DMSO. Structures of the synthesized compounds were elucidated by infrared IR ultraviolet VV mass spectrometry MS and nuclear magnetic resonance IB NMR spectroscopic methods. The anti-multidrug resistant Staphylococcus aureus MRSA activity of 4 -ethoxy-5 7-dimethoxyflavone and its corresponding chalcone were performed in vitro using the minimum inhibitory concentration MIC value determination assay and efflux assay.
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Abstract
In the present study a derivative of apigenin namely 4-ethoxy-5 7 dimethoxyflavone has been synthesized from phioroacetophenone via its chalcone precursor followed by the treatment of iodine in dimethylsulfoxide DMSO. Structures of the synthesized compounds were elucidated by infrared IR ultraviolet VV mass spectrometry MS and nuclear magnetic resonance IB NMR spectroscopic methods. The anti-multidrug resistant Staphylococcus aureus MRSA activity of 4 -ethoxy-5 7-dimethoxyflavone and its corresponding chalcone were performed in vitro using the minimum inhibitory concentration MIC value determination assay and efflux assay.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal QK99 M3S471 2008 Call Number |
| AGROVOC Term: | FLAVONOIDS |
| AGROVOC Term: | INFRARED RADIATION |
| AGROVOC Term: | INFRARED SPECTROPHOTOMETRY |
| AGROVOC Term: | ULTRAVIOLET IRRADIATION |
| AGROVOC Term: | ULTRAVIOLET SPECTROPHOTOMETRY |
| AGROVOC Term: | MASS SPECTROMETRY |
| AGROVOC Term: | MALAYSIA |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:14 |
| URI: | http://webagris.upm.edu.my/id/eprint/11372 |
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