Citation
Rofiee M.S., . and Somchit M. N., . and Sulaiman M. R., . and Long K., . and Zakaria Z. A., . (2010) Hepatoprotective properties of MARDI-produced virgin coconut oil. [Proceedings Paper]
Abstract
The present study aimed to determine the hepatoprotective effect of MARDI-produced virgin coconut oils using the paracetamol-induced liver damage in rats. Liver injury induced by 3 g/kg paracetamol increased the liver weight per 100 g bodyweight indicating liver damage. Histological observation also confirmed liver damage indicated by the presence of inflammations and necrosis on the respective liver section. Interestingly pretreatment of the rats with 10 but not 1 and 5 ml/kg of both VCO significantly reduced the liver damage caused by the administration of paracetamol which is confirmed by the histological sections. In conclusion VCO possessed hepatoprotective effect that requires further in-depth study.
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Abstract
The present study aimed to determine the hepatoprotective effect of MARDI-produced virgin coconut oils using the paracetamol-induced liver damage in rats. Liver injury induced by 3 g/kg paracetamol increased the liver weight per 100 g bodyweight indicating liver damage. Histological observation also confirmed liver damage indicated by the presence of inflammations and necrosis on the respective liver section. Interestingly pretreatment of the rats with 10 but not 1 and 5 ml/kg of both VCO significantly reduced the liver damage caused by the administration of paracetamol which is confirmed by the histological sections. In conclusion VCO possessed hepatoprotective effect that requires further in-depth study.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Summary En |
| AGROVOC Term: | Fermented products |
| AGROVOC Term: | Coconut oil |
| AGROVOC Term: | Functional foods |
| AGROVOC Term: | Health foods |
| AGROVOC Term: | Research and development |
| AGROVOC Term: | Toxicity |
| AGROVOC Term: | Laboratory experimentation |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:14 |
| URI: | http://webagris.upm.edu.my/id/eprint/11407 |
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