Citation
Aida Azlina A., . and Qodriyah H. M. S., . and Nur Azlina M. F., . and Farihah H. S., . (2008) Effects of Piper sarmentosum extract and glycyrrhizic acid on blood pressure and body weight in ovariectomized rats. [Proceedings Paper]
Abstract
This study was conducted in order to evaluate the effects of Piper sarmentosum PS extract and glycyrrhizic acid GCA on blood pressure and body weight in ovariectomized rats. Twenty-eight female SpragueDawley rats were randomly divided into four groups. Three groups were ovariectomized OVX while the remaining group undergoes sham operation. The OVX groups were given PS extract GCA and water WTR respectively while the sham-operated SHM group received water only. Blood pressure was measured monthly while body weight was taken weekly. Our findings showed that OVX rats had a significant increased in body weight after 3 months compared to the SHM group. Meanwhile for blood pressure the GCA group was significantly higher after 3 months of treatment compared to PS group which confirmed the hypothesis that GCA increases the blood pressure. In conclusion GCA but not PS extract has effect on blood pressure while both GCA and PS extract were unable to reduce the increased body weight in OVX rats.
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Abstract
This study was conducted in order to evaluate the effects of Piper sarmentosum PS extract and glycyrrhizic acid GCA on blood pressure and body weight in ovariectomized rats. Twenty-eight female SpragueDawley rats were randomly divided into four groups. Three groups were ovariectomized OVX while the remaining group undergoes sham operation. The OVX groups were given PS extract GCA and water WTR respectively while the sham-operated SHM group received water only. Blood pressure was measured monthly while body weight was taken weekly. Our findings showed that OVX rats had a significant increased in body weight after 3 months compared to the SHM group. Meanwhile for blood pressure the GCA group was significantly higher after 3 months of treatment compared to PS group which confirmed the hypothesis that GCA increases the blood pressure. In conclusion GCA but not PS extract has effect on blood pressure while both GCA and PS extract were unable to reduce the increased body weight in OVX rats.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal RM666 H33 B573 Call Number |
| AGROVOC Term: | Piper |
| AGROVOC Term: | Piperaceae |
| AGROVOC Term: | Animal models |
| AGROVOC Term: | Blood pressure |
| AGROVOC Term: | Leaves |
| AGROVOC Term: | Freeze-drying |
| AGROVOC Term: | Laboratory animals |
| AGROVOC Term: | Body weight |
| AGROVOC Term: | Statistical analysis |
| AGROVOC Term: | Obesity |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:15 |
| URI: | http://webagris.upm.edu.my/id/eprint/12846 |
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