Carbazole alkaloids from curry leaf tree Murraya koenigii and its larvicidal activity


Citation

Ee Gwendoline Cheng Lian, . and Noor Haslizawati Abu Bakar, . and Marwardi Rahmani, . and Mohd. Aspollah Sukari, . and Nurul Waznah Mohd. Sharif, . and Atan Md. Sharif, . (2008) Carbazole alkaloids from curry leaf tree Murraya koenigii and its larvicidal activity. [Proceedings Paper]

Abstract

Curry leaf tree Murraya koenigi L. Spreng. has an aromatic smell which are normally used as natural flavoring in curries and commonly found in India and Peninsular Asia. Curry leaf tree is known to be the richest source of carbazole alkaloids. The dried ground of the stem barks and roots were soaked in various solvents hexane chloroform and methanol to give different types of crude extracts. The separation of crude extracts was carried out using chromatographic techniques. The isolated compounds were identified as mahanimbine 1 girinimbine 2 murrayanine 3 murrayafoline-A 4 3-methylcarbazole 5 and bsitosterol 6. The structures of these compounds were established using infrared spectroscopy lR mass spectrometry MS and nuclear magnetic resonance NMR techniques. The crude extracts of the plant were tested against the larvae of Aedes aegypti. The LC50 and LC90values of the bioassays showed that the crude extracts were strongly toxic to the larvae of A. aegypti.


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Abstract

Curry leaf tree Murraya koenigi L. Spreng. has an aromatic smell which are normally used as natural flavoring in curries and commonly found in India and Peninsular Asia. Curry leaf tree is known to be the richest source of carbazole alkaloids. The dried ground of the stem barks and roots were soaked in various solvents hexane chloroform and methanol to give different types of crude extracts. The separation of crude extracts was carried out using chromatographic techniques. The isolated compounds were identified as mahanimbine 1 girinimbine 2 murrayanine 3 murrayafoline-A 4 3-methylcarbazole 5 and bsitosterol 6. The structures of these compounds were established using infrared spectroscopy lR mass spectrometry MS and nuclear magnetic resonance NMR techniques. The crude extracts of the plant were tested against the larvae of Aedes aegypti. The LC50 and LC90values of the bioassays showed that the crude extracts were strongly toxic to the larvae of A. aegypti.

Additional Metadata

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Item Type: Proceedings Paper
Additional Information: Available at Perpustakaan Sultan Abdul Samad Uni-versiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal RM666 H33 B573 Call Number
AGROVOC Term: Murraya koenigii
AGROVOC Term: Rutaceae
AGROVOC Term: Medicinal plants
AGROVOC Term: Alkaloids
AGROVOC Term: Chemical composition
AGROVOC Term: Aedes aegypti
AGROVOC Term: Larvae
AGROVOC Term: Plant extracts
AGROVOC Term: Isolation
AGROVOC Term: Extraction
Geographical Term: MALAYSIA
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 24 Apr 2025 05:15
URI: http://webagris.upm.edu.my/id/eprint/12863

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