Citation
Nor Hadiani Ismail, . and Dzulsuhaimi Daud, . and Faridahanim Mohd Jaafar, . and Abdul Rashid Li, . (2008) Antidiabetic effect of Leucaena leucocephala ethanolic extract on alloxan-induced diabetic rats. [Proceedings Paper]
Abstract
Leucaena leucocephala Lam. de Wit or locally known as ;petai belalang; is a free-seeding colonizing plant which has spread to a very wide range of sites and can be found commonly throughout Malaysia. Traditional practitioners used its leaves and pods for diabetic disease and a decoction of roots and barks is taken as contraceptive ecbolic depilatory or emmenagogue. In the current study the ethanolic extracts of Leucaena leucocephala barks and leaves were tested for their hypoglycaemic activity. Control and alloxan induced diabetic rats were treated orally either with vehicle Leucaena leucocephala leaf and bark ethanolic extracts once daily for three weeks respectively. Daily administration of Leucaena leucocephala significantly reduced the blood glucose level p 0.001. The results also showed that alloxan caused body weight reduction significantly p 0.001 which is stabilized by the ethanolic extract of Leucaena leucocephala. The observed results indicate that Leucaena leucocephala bark and leaf ethanolic extracts possess hypoglycaemic effect.
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Abstract
Leucaena leucocephala Lam. de Wit or locally known as ;petai belalang; is a free-seeding colonizing plant which has spread to a very wide range of sites and can be found commonly throughout Malaysia. Traditional practitioners used its leaves and pods for diabetic disease and a decoction of roots and barks is taken as contraceptive ecbolic depilatory or emmenagogue. In the current study the ethanolic extracts of Leucaena leucocephala barks and leaves were tested for their hypoglycaemic activity. Control and alloxan induced diabetic rats were treated orally either with vehicle Leucaena leucocephala leaf and bark ethanolic extracts once daily for three weeks respectively. Daily administration of Leucaena leucocephala significantly reduced the blood glucose level p 0.001. The results also showed that alloxan caused body weight reduction significantly p 0.001 which is stabilized by the ethanolic extract of Leucaena leucocephala. The observed results indicate that Leucaena leucocephala bark and leaf ethanolic extracts possess hypoglycaemic effect.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Uni-versiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal RM666 H33 B573 Call Number |
| AGROVOC Term: | Leucaena leucocephala |
| AGROVOC Term: | Fabaceae |
| AGROVOC Term: | Medicinal plants |
| AGROVOC Term: | Disease treatment |
| AGROVOC Term: | Blood sugar |
| AGROVOC Term: | Diabetes mellitus |
| AGROVOC Term: | Animal models |
| AGROVOC Term: | Dosage |
| AGROVOC Term: | Dosage effects |
| AGROVOC Term: | Leaves |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:15 |
| URI: | http://webagris.upm.edu.my/id/eprint/12866 |
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