Citation
Ismail J., . and Nur Diyana Ishak, . and Zani Assim, . (2011) Antifungal activity of Jatropha curcas pericarps and leaves extracts. [Proceedings Paper]
Abstract
Jatropha curcas usually have a variety of uses especially in traditional medicine such as to relieve pain and skin disease. The oil and aqueous extracts from all parts of plants have the potential to act as insecticide. The objectives of this study were to determine toxicity methanol extracts of J. curcas leaves and pericarps; and to analyse the chemical composition of J. curcas pericarps and leaves. Various concentration levels of methanol crude extracts of pericarps and leaves 50 g/mL 100 g/mL 250 g/mL 500 g/mL and 1000 g/mL were prepared. The extracts were subjected to analysis on capillary GC/MS to determine the chemical constituents. Antifungal activities were determined by using paper disc diffusion method and the antifungal activities were evaluated after 72 h of incubation period. This study revealed that the leaves and pericarp extracts possessed significant activities against Trametes versicolor Gleophy/lum trabeum and Chaetomium globosum. Leaves and pericarps extracts showed antifungal activity against T. versicolor at 500 g/mL At the concentration of 1000 g/mL leaves and pericarps extracts it exhibited weak to moderate antifungal activity for T. versicolor G. trabeum and C. globosum. The major components of hexane and dichloromethane DCM soluble fraction of methanol extract from pericarps and leaves were 9-octadecanoic acid hexacosane 1 2- benzenedicarboxylic acid mono 2-ethyihexyl ester and octacosane. The results suggest that J. curcas methanol extracts have weak to moderate antifungal activity against T. versicolor G. trabeum and C. globosum. Further studies on antifungal and antibacterial activities are required in order to diversify the utilization of J. curcas plant.
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Abstract
Jatropha curcas usually have a variety of uses especially in traditional medicine such as to relieve pain and skin disease. The oil and aqueous extracts from all parts of plants have the potential to act as insecticide. The objectives of this study were to determine toxicity methanol extracts of J. curcas leaves and pericarps; and to analyse the chemical composition of J. curcas pericarps and leaves. Various concentration levels of methanol crude extracts of pericarps and leaves 50 g/mL 100 g/mL 250 g/mL 500 g/mL and 1000 g/mL were prepared. The extracts were subjected to analysis on capillary GC/MS to determine the chemical constituents. Antifungal activities were determined by using paper disc diffusion method and the antifungal activities were evaluated after 72 h of incubation period. This study revealed that the leaves and pericarp extracts possessed significant activities against Trametes versicolor Gleophy/lum trabeum and Chaetomium globosum. Leaves and pericarps extracts showed antifungal activity against T. versicolor at 500 g/mL At the concentration of 1000 g/mL leaves and pericarps extracts it exhibited weak to moderate antifungal activity for T. versicolor G. trabeum and C. globosum. The major components of hexane and dichloromethane DCM soluble fraction of methanol extract from pericarps and leaves were 9-octadecanoic acid hexacosane 1 2- benzenedicarboxylic acid mono 2-ethyihexyl ester and octacosane. The results suggest that J. curcas methanol extracts have weak to moderate antifungal activity against T. versicolor G. trabeum and C. globosum. Further studies on antifungal and antibacterial activities are required in order to diversify the utilization of J. curcas plant.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. QR22 M3I61 2011 vol.2 Call Number. |
| AGROVOC Term: | Jatropha curcas |
| AGROVOC Term: | Euphorbiaceae |
| AGROVOC Term: | Fractionation |
| AGROVOC Term: | Gas chromatography |
| AGROVOC Term: | Mass spectrometry |
| AGROVOC Term: | Pericarp |
| AGROVOC Term: | Leaves |
| AGROVOC Term: | Plant extracts |
| AGROVOC Term: | Chemical composition |
| AGROVOC Term: | Inhibition |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:15 |
| URI: | http://webagris.upm.edu.my/id/eprint/12948 |
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