Citation
Siew K. Y., . and Wong S. K., . (2010) Antimicrobial properties and brine shrimp toxicity of anti-cancer herbs; Pereskia bleo Pereskia grandifolia and Strobilanthes crispus. [Proceedings Paper]
Abstract
Pereskia bleo Pereskia grandifolia and Strobilanthes crispus are widely recognized as anti-cancer herbs among local community. The antimicrobial properties and toxicity of these herbs were analysed. Aqueous extraction using both blending and decoction methods were used to obtain the herb crude extracts. Antibacterial susceptible testing of the extracts was done using disc diffusion and minimum inhibition concentration MIC techniques. Toxicity test against brine shrimps was performed to determine the lethal dose LD‚0 of those plant extracts. All the crude extracts of P. bleo P. grandifolia and S. crispus did not show any antibacterial activities against Escherichia coli Klebsiella pneumonia Staphylococcus aureus and Pseudomonas aeruginosa at amount up to 1000 ppm for MIC and 200 g in disc diffusion. P. bleo and S. crispus showed LC‚0 values beyond 1000 ppm. The LC‚0 value of blended and decocted extracts of P. grandifolia was 13.34 g/ml and 66.07 /ml respectively.
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Abstract
Pereskia bleo Pereskia grandifolia and Strobilanthes crispus are widely recognized as anti-cancer herbs among local community. The antimicrobial properties and toxicity of these herbs were analysed. Aqueous extraction using both blending and decoction methods were used to obtain the herb crude extracts. Antibacterial susceptible testing of the extracts was done using disc diffusion and minimum inhibition concentration MIC techniques. Toxicity test against brine shrimps was performed to determine the lethal dose LD‚0 of those plant extracts. All the crude extracts of P. bleo P. grandifolia and S. crispus did not show any antibacterial activities against Escherichia coli Klebsiella pneumonia Staphylococcus aureus and Pseudomonas aeruginosa at amount up to 1000 ppm for MIC and 200 g in disc diffusion. P. bleo and S. crispus showed LC‚0 values beyond 1000 ppm. The LC‚0 value of blended and decocted extracts of P. grandifolia was 13.34 g/ml and 66.07 /ml respectively.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. TP248.14 I61 2008 Call Number. |
| AGROVOC Term: | Cactaceae |
| AGROVOC Term: | Acanthaceae |
| AGROVOC Term: | Medicinal herbs |
| AGROVOC Term: | Antimicrobial properties |
| AGROVOC Term: | Plant extracts |
| AGROVOC Term: | Cancer disease |
| AGROVOC Term: | Toxicity |
| AGROVOC Term: | Blending |
| AGROVOC Term: | Klebsiella pneumoniae |
| AGROVOC Term: | Escherichia coli |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:15 |
| URI: | http://webagris.upm.edu.my/id/eprint/13156 |
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