Orego-Stim: The proven and researched alternative to infeed antibiotic growth promoters and coccidiostats

Tan Justin Yu Wen, . (2007) Orego-Stim: The proven and researched alternative to infeed antibiotic growth promoters and coccidiostats. [Proceedings Paper]

Orego-Stim is a 100 natural phytogenic feed additive containing oregano essential oil extracted from a specific chemotype of Origanum vulgare ssp. hirtum which is derived from a hybrid plant-breeding programme and grown commercially under strictly-controlled plantation conditions. The composition of the oil consists predominantly of a unique ratio and concentration of the natural phenolic compounds carvacrol and thymol which are known to be powerful antimicrobial agents. Orego-Stim has also been proven to contain anticoccidial properties. The phenolic compounds in Orego-Stim disrupt the life cycle of coccidian parasites by speeding up the rate of shedding of the gut lining. Through this mode of action intracellular coccidial sporozoites are shed before they have the opportunity to penetrate deeper into the gut wall or form new oocysts. Clinical coccidiosis is therefore prevented or controlled by creating an environment that is hostile to the completion of the life cycle of the parasite. This mode of action is similar to that of ionophores such as salinomycin and monensin that have been used as antibiotic growth promoters as well as coccidiostats worldwide. In contrast to antibiotic growth promoters and coccidiostats there has been no evidence of development of bacterial resistance from using Orego-Stim simply because its inhibitory effect on bacteria is due to its phenolic mode of action and not through the transfer of any chromosomes. The components in oregano oil are classified by the FDA as generally recognised as safe GRAS. Orego-Stim is not absorbed through the intestines into the bloodstream so there are no residues in livestock products such as meat milk and eggs. This means that no withdrawal period is necessary and Orego-Stim can be used right up to the slaughter time. Orego-Stim has been shown to improve palatability feed intake FCR and growth rates. Extensive in vitro and in vivo trials have proven that Orego-Stim assists in alleviating problems associated with the presence of gastrointestinal pathogens such as E. coli Salmonella spp. Clostridium perfringens Lawsonia intracellularis and Eimeria spp.

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Abstract

Orego-Stim is a 100 natural phytogenic feed additive containing oregano essential oil extracted from a specific chemotype of Origanum vulgare ssp. hirtum which is derived from a hybrid plant-breeding programme and grown commercially under strictly-controlled plantation conditions. The composition of the oil consists predominantly of a unique ratio and concentration of the natural phenolic compounds carvacrol and thymol which are known to be powerful antimicrobial agents. Orego-Stim has also been proven to contain anticoccidial properties. The phenolic compounds in Orego-Stim disrupt the life cycle of coccidian parasites by speeding up the rate of shedding of the gut lining. Through this mode of action intracellular coccidial sporozoites are shed before they have the opportunity to penetrate deeper into the gut wall or form new oocysts. Clinical coccidiosis is therefore prevented or controlled by creating an environment that is hostile to the completion of the life cycle of the parasite. This mode of action is similar to that of ionophores such as salinomycin and monensin that have been used as antibiotic growth promoters as well as coccidiostats worldwide. In contrast to antibiotic growth promoters and coccidiostats there has been no evidence of development of bacterial resistance from using Orego-Stim simply because its inhibitory effect on bacteria is due to its phenolic mode of action and not through the transfer of any chromosomes. The components in oregano oil are classified by the FDA as generally recognised as safe GRAS. Orego-Stim is not absorbed through the intestines into the bloodstream so there are no residues in livestock products such as meat milk and eggs. This means that no withdrawal period is necessary and Orego-Stim can be used right up to the slaughter time. Orego-Stim has been shown to improve palatability feed intake FCR and growth rates. Extensive in vitro and in vivo trials have proven that Orego-Stim assists in alleviating problems associated with the presence of gastrointestinal pathogens such as E. coli Salmonella spp. Clostridium perfringens Lawsonia intracellularis and Eimeria spp.

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Item Type:	Proceedings Paper
Additional Information:	Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. SF94.6 I61 2006 Call Number.
AGROVOC Term:	Plant products
AGROVOC Term:	Oregano
AGROVOC Term:	Feed additives
AGROVOC Term:	antimicrobial agents
AGROVOC Term:	Feed intake
AGROVOC Term:	Broilers
AGROVOC Term:	Gastrointestinal diseases
AGROVOC Term:	Feed conversion efficiency
AGROVOC Term:	Growth rate
AGROVOC Term:	Mortality
Geographical Term:	MALAYSIA
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 05:16
URI:	http://webagris.upm.edu.my/id/eprint/13696

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