Preliminary studies on the amino acid sequences of some Malayan cobra Naja naja sputatrix venom toxins Malaysia

Tan N.H., . and Arunmozhiarasi Armugam, . and Chung M.C.M., . (1993) Preliminary studies on the amino acid sequences of some Malayan cobra Naja naja sputatrix venom toxins Malaysia. [Proceedings Paper]

Two major neurotoxins sputatoxin-1 and sputatoxin-2 and two lethal phospholipase A enzymes sputatrix PLA2-1 and sputatrix PLA2-2 were isolated from Malayan cobra Naja naja sputatrix venom using gel filtration chromatography ion exchange chromatography followed by reversed phase HPLC and subjected to sequencing using the Edman procedure. The partial N-terminal amino acid sequences of these toxins were: sputatoxin-1; LECHDQQSSQTPTTT-GCSGG; sputatoxin-2: LECHNQQSSQAPTTTTCSGG; sputatrix PLA2-1 and PLA2-2: NLYQFKNMIQCTVPNRSWWH

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Abstract

Two major neurotoxins sputatoxin-1 and sputatoxin-2 and two lethal phospholipase A enzymes sputatrix PLA2-1 and sputatrix PLA2-2 were isolated from Malayan cobra Naja naja sputatrix venom using gel filtration chromatography ion exchange chromatography followed by reversed phase HPLC and subjected to sequencing using the Edman procedure. The partial N-terminal amino acid sequences of these toxins were: sputatoxin-1; LECHDQQSSQTPTTT-GCSGG; sputatoxin-2: LECHNQQSSQAPTTTTCSGG; sputatrix PLA2-1 and PLA2-2: NLYQFKNMIQCTVPNRSWWH

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Item Type:	Proceedings Paper
Additional Information:	Summaries En Ms
AGROVOC Term:	CULEBRA
AGROVOC Term:	CROMATOGRAFIA LIQUIDA ALTA PRESION
AGROVOC Term:	AMINOACIDOS
AGROVOC Term:	VENENOS
AGROVOC Term:	MALASIA
Geographical Term:	MALAYSIA
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:26
URI:	http://webagris.upm.edu.my/id/eprint/15441

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