Anti-inflammatory activities of several Malaysian medicinal plants

Rasadah Mat Ali, . and Nik Musa'adah Mustapaha, . and Ling Sui Kiong, . and Ong Boo Kean, . and Azie Aida Ahmad, . (2002) Anti-inflammatory activities of several Malaysian medicinal plants. [Proceedings Paper]

Thirteen species of Malaysian medicinal plants were examined for their anti-inflammatory activities using the in vitro lipoxygenase hyaluronidase and platelet- activating factor PAF receptor binding antagonist and in vivo tetradecanoylphorbol aceatate TPA induced mouse ear oedema assays. These techniques are frequently used to access the anti-inflammatory effect of natural products. Leaf extracts of Lantana camara was found to exhibit strong inhibition in the TPA model and PAF receptor binding assay. Piper betle exhibited both in vitro lipoxygenase and in vivo TPA model anti-inflammatory activities.

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Abstract

Thirteen species of Malaysian medicinal plants were examined for their anti-inflammatory activities using the in vitro lipoxygenase hyaluronidase and platelet- activating factor PAF receptor binding antagonist and in vivo tetradecanoylphorbol aceatate TPA induced mouse ear oedema assays. These techniques are frequently used to access the anti-inflammatory effect of natural products. Leaf extracts of Lantana camara was found to exhibit strong inhibition in the TPA model and PAF receptor binding assay. Piper betle exhibited both in vitro lipoxygenase and in vivo TPA model anti-inflammatory activities.

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Item Type:	Proceedings Paper
Additional Information:	1 table
AGROVOC Term:	ANTIINFLAMMATORY AGENTS
AGROVOC Term:	LIPOXYGENASE
AGROVOC Term:	PLATELETS
AGROVOC Term:	BACTERIAL PESTICIDES
AGROVOC Term:	PIPER BETLE
AGROVOC Term:	INFLAMMATION
AGROVOC Term:	DRUG PLANTS
AGROVOC Term:	MALAYSIA
Geographical Term:	MALAYSIA
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:26
URI:	http://webagris.upm.edu.my/id/eprint/15533

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