Citation
Yassir M. A., . and Arifah A. K., . and Zuraini A., . and Yaakub H., . and Z.A. Zakaria, . and M.N. Somchit, . (2009) Antioxidant activity of conjugated linoleic acid isomers. [Proceedings Paper]
Abstract
Conjugated linoleic acids CLAs are a mixture of positional and geometric isomers of linoleic acid LA containing conjugated double bonds. It have been well known as having many diverse biological activities including anti-carcinogenic antioxidant anti-atherosclerotic anti-obesity anti-diabetic and immune system enhancement. Therefore this study was undertaken to investigate the free radical scavenging properties oftrans- 10 cis-12 and cis-9 trans-11 CLA isomers against the stable 2 2-diphenyl-l-picryhydrazyl radical DPPH in ethanol by using an ELISA reader technique. The results showed that CLA directly reacted and quenched free DPPH radicals. Dose and time effects of CLA-DPPH reactions were observed without any lag phase. Additionally the total antioxidant capacity TAC of trans-10 cis-12 was higher than that of cis-9 transe-11 under same experimental condition. This study indicates that the beneficial health effects of CLA isomers my attributed to their radical scavenging properties.
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Abstract
Conjugated linoleic acids CLAs are a mixture of positional and geometric isomers of linoleic acid LA containing conjugated double bonds. It have been well known as having many diverse biological activities including anti-carcinogenic antioxidant anti-atherosclerotic anti-obesity anti-diabetic and immune system enhancement. Therefore this study was undertaken to investigate the free radical scavenging properties oftrans- 10 cis-12 and cis-9 trans-11 CLA isomers against the stable 2 2-diphenyl-l-picryhydrazyl radical DPPH in ethanol by using an ELISA reader technique. The results showed that CLA directly reacted and quenched free DPPH radicals. Dose and time effects of CLA-DPPH reactions were observed without any lag phase. Additionally the total antioxidant capacity TAC of trans-10 cis-12 was higher than that of cis-9 transe-11 under same experimental condition. This study indicates that the beneficial health effects of CLA isomers my attributed to their radical scavenging properties.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | 2ill. 4 ref. |
| AGROVOC Term: | Linoleic acid |
| AGROVOC Term: | Antioxidants |
| AGROVOC Term: | Free radicals |
| AGROVOC Term: | Isomerose |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Norfaezah Khomsan |
| Last Modified: | 24 Apr 2025 05:27 |
| URI: | http://webagris.upm.edu.my/id/eprint/15840 |
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