Microfilaricidal activity of Xylocarpus granatum Meliaceae against subperiodic Brugia malayi


Citation

Zaridah M.Z., . and Syed Zahir Idid, . and Wan Omar A., . and Khozirah S., . (2001) Microfilaricidal activity of Xylocarpus granatum Meliaceae against subperiodic Brugia malayi. [Proceedings Paper]

Abstract

Xylocarpus granatum Koenig Meliaceae known as cannonball mangrove or 'nyireh bunga' are locally common in mangrove swamps along Malaysian coast and can be found in tidal mud especially towards their upper limits. In this study three aqueous extracts from three different plant parts of Xylocarpus granatum Meliaceae were tested in vitro against microfilariae of subperiodic Brugia malayi the causative agent of lymphatic filariasis in Malaysia. The three plant parts were dried seeds SX dried husks HX and dried leaves LX. The relative movability RM value of the worms over the 24-hour observation period was used as a measure of the microfilaricidal activity of the three aqueous extracts. Using non-linear regression analysis the microfilaricidal activities of the three extracts were determined. Based on the results of the analysis SX gave the strongest activity against microfilariae of subperiodic B. malayi followed by LX and HX.


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Abstract

Xylocarpus granatum Koenig Meliaceae known as cannonball mangrove or 'nyireh bunga' are locally common in mangrove swamps along Malaysian coast and can be found in tidal mud especially towards their upper limits. In this study three aqueous extracts from three different plant parts of Xylocarpus granatum Meliaceae were tested in vitro against microfilariae of subperiodic Brugia malayi the causative agent of lymphatic filariasis in Malaysia. The three plant parts were dried seeds SX dried husks HX and dried leaves LX. The relative movability RM value of the worms over the 24-hour observation period was used as a measure of the microfilaricidal activity of the three aqueous extracts. Using non-linear regression analysis the microfilaricidal activities of the three extracts were determined. Based on the results of the analysis SX gave the strongest activity against microfilariae of subperiodic B. malayi followed by LX and HX.

Additional Metadata

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Item Type: Proceedings Paper
Additional Information: Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. QD415 A1N277 2000
AGROVOC Term: MELIACEAE
AGROVOC Term: BRUGIA MALAYI
AGROVOC Term: PLANT EXTRACTS
AGROVOC Term: SEEDS
AGROVOC Term: HUSKS
AGROVOC Term: LEAVES
AGROVOC Term: IN VITRO
AGROVOC Term: CULICIDAE
AGROVOC Term: ISOLATION
AGROVOC Term: PARASITES
Geographical Term: MALAYSIA
Depositing User: Ms. Norfaezah Khomsan
Last Modified: 24 Apr 2025 05:27
URI: http://webagris.upm.edu.my/id/eprint/15920

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