Citation
Nor Azah Mohd. Ali, . and Mawardi Rahmani, . and A. Manaf Ali, . and Khozirah Shaari, . and Mastura Mohtar, . (2001) Antimicrobial activity of Cinnamomum impressicostatum. [Proceedings Paper]
Abstract
The essential oils and extracts hexane chloroform and methanol of the leaf and stem bark of C.impressicostatum were assayed against three types of microorganisms i.e: Gram-positive bacteria Gram-negative bacteria and fungi including yeast candidas and dermatophytes. The essential oils exhibited moderate antifungal activity towards Candida alicans Microsporum canis Trichophyton mentagrophytes and T. rubrum with MIC values of 2.50 microgram/micralitre. The hexane extract showed strong antifungal activity i.d.15.0mm against Candida albicans Candida lipolytica and Microsporum canis. The chloroform extract showed the greatest activity over a wide spectrum of microorganisms. The hexane and chloroform extracts contained similar chemical components which are identified as safrole methyl cinnamate and 3-3 4-methylenedioxyphenyl propenal. Methyl cinnamate which represented 60 per cent of the total bark oil of C. impressicostatum exhibited significant activity against Candida albicans C. lipolytica Saccharomyces cerevisiae Microsporum canis and Bacillus cereus with a MIC value of 1.25 microgram/micralitre. This suggest that the overall activity of the hexane and chloroform extracts were probably due to the large amount of mehyl cinnamate present in them.
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Abstract
The essential oils and extracts hexane chloroform and methanol of the leaf and stem bark of C.impressicostatum were assayed against three types of microorganisms i.e: Gram-positive bacteria Gram-negative bacteria and fungi including yeast candidas and dermatophytes. The essential oils exhibited moderate antifungal activity towards Candida alicans Microsporum canis Trichophyton mentagrophytes and T. rubrum with MIC values of 2.50 microgram/micralitre. The hexane extract showed strong antifungal activity i.d.15.0mm against Candida albicans Candida lipolytica and Microsporum canis. The chloroform extract showed the greatest activity over a wide spectrum of microorganisms. The hexane and chloroform extracts contained similar chemical components which are identified as safrole methyl cinnamate and 3-3 4-methylenedioxyphenyl propenal. Methyl cinnamate which represented 60 per cent of the total bark oil of C. impressicostatum exhibited significant activity against Candida albicans C. lipolytica Saccharomyces cerevisiae Microsporum canis and Bacillus cereus with a MIC value of 1.25 microgram/micralitre. This suggest that the overall activity of the hexane and chloroform extracts were probably due to the large amount of mehyl cinnamate present in them.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Summary En |
| AGROVOC Term: | CINNAMOMUM |
| AGROVOC Term: | ESSENTIAL OILS |
| AGROVOC Term: | PLANT EXTRACTS |
| AGROVOC Term: | ANTIMICROBIAL PROPERTIES |
| AGROVOC Term: | GRAM NEGATIVE BACTERIA |
| AGROVOC Term: | GRAM POSITIVE BACTERIA |
| AGROVOC Term: | FUNGI |
| AGROVOC Term: | ANTIFUNGAL PROPERTIES |
| AGROVOC Term: | MALAYSIA |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Norfaezah Khomsan |
| Last Modified: | 24 Apr 2025 05:27 |
| URI: | http://webagris.upm.edu.my/id/eprint/15923 |
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