Major chemical constituents from the leaves of Cinnamomum mollisimum Lauraceae


Citation

Zakaria Bahari, . and Muhammad Nasri Abdul Rahman, . (2001) Major chemical constituents from the leaves of Cinnamomum mollisimum Lauraceae. [Proceedings Paper]

Abstract

Isolation and characterisation of the major chemical constituents from the leaves of Cinnamomum mollisimum has been carried out. The extractions were carried out using soxhlet techniques with petroleum eter ethyl acetate and methanol successively. Each extract was subjected to column chromatography to afford the pure compounds. The structures of these compounds were determined by various spectroscopic methods such as ultraviolet UV infrared IR nuclear magnetic resonance H and C NMR and gas chromatography coupled with mass spectrometry GC-MS. Based on these spectroscopic analysis it was concluded that the compound from EtOAc extract was benzoic acid while benzyl benzoate was isolated the MeOH extract. Brine shrimp lethality assay was tested on EtOAc and MeOH extracts and also on the pure compounds of benzoic acid and benzyl benzoate. Benzoic acid ED501.7 ppm was found to be more toxic than benzyl benzoat ED5013.85 ppm and other extracts.


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Abstract

Isolation and characterisation of the major chemical constituents from the leaves of Cinnamomum mollisimum has been carried out. The extractions were carried out using soxhlet techniques with petroleum eter ethyl acetate and methanol successively. Each extract was subjected to column chromatography to afford the pure compounds. The structures of these compounds were determined by various spectroscopic methods such as ultraviolet UV infrared IR nuclear magnetic resonance H and C NMR and gas chromatography coupled with mass spectrometry GC-MS. Based on these spectroscopic analysis it was concluded that the compound from EtOAc extract was benzoic acid while benzyl benzoate was isolated the MeOH extract. Brine shrimp lethality assay was tested on EtOAc and MeOH extracts and also on the pure compounds of benzoic acid and benzyl benzoate. Benzoic acid ED501.7 ppm was found to be more toxic than benzyl benzoat ED5013.85 ppm and other extracts.

Additional Metadata

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Item Type: Proceedings Paper
Additional Information: Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. QD415 A1N277 2000
AGROVOC Term: CINNAMOMUM
AGROVOC Term: LAURACEAE
AGROVOC Term: LEAVES
AGROVOC Term: CHEMICAL COMPOSITION
AGROVOC Term: EXTRACTS
AGROVOC Term: CHROMATOGRAPHY
AGROVOC Term: ULTRAVIOLET RADIATION
AGROVOC Term: INFRARED RADIATION
AGROVOC Term: NMR SPECTROSCOPY
AGROVOC Term: MALAYSIA
Geographical Term: MALAYSIA
Depositing User: Ms. Norfaezah Khomsan
Last Modified: 24 Apr 2025 05:27
URI: http://webagris.upm.edu.my/id/eprint/15949

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