Recent advances in molecular basis of follicular growth and oocyte maturation - use of farm animals for biology and biomedical science

Sato E., . (2004) Recent advances in molecular basis of follicular growth and oocyte maturation - use of farm animals for biology and biomedical science. [Proceedings Paper]

The birth of clone animals if influencing the frontier of research in animal biotechnology. It has effected animal biotechnology research by necessitating setting of new research subjects and modification of the strategies of ongoing research projects and challenges ventures in areas formerly considered impossible. This paper discusses topics such mass production of fertile ova and oocyte maturation. Oocytes are needed for the production of a clone by nuclear transplantation. Mitochondrial DNA inherited via the oocycte are involved also in the morphogenesis. Therefore oocyctes from the same animal must be used as recipients to produce genuine clones by nuclear transplantation. Experimenting on the assumption that selective oogenesis can be avoided and apoptosis of oocytes can be prevented by using ovarian angiogenic factors will be introduced. It is important to clarify the factors of oocytes involved in reprogramming of somatic cells. Such factors are tought to be expressed in oocytes during oogenesis and oocyte maturation. Therefore molecular mechanisms of oogenesis and oocyte maturation must be clarified extensively. Topics in this field including recent advances will be discussed.

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Abstract

The birth of clone animals if influencing the frontier of research in animal biotechnology. It has effected animal biotechnology research by necessitating setting of new research subjects and modification of the strategies of ongoing research projects and challenges ventures in areas formerly considered impossible. This paper discusses topics such mass production of fertile ova and oocyte maturation. Oocytes are needed for the production of a clone by nuclear transplantation. Mitochondrial DNA inherited via the oocycte are involved also in the morphogenesis. Therefore oocyctes from the same animal must be used as recipients to produce genuine clones by nuclear transplantation. Experimenting on the assumption that selective oogenesis can be avoided and apoptosis of oocytes can be prevented by using ovarian angiogenic factors will be introduced. It is important to clarify the factors of oocytes involved in reprogramming of somatic cells. Such factors are tought to be expressed in oocytes during oogenesis and oocyte maturation. Therefore molecular mechanisms of oogenesis and oocyte maturation must be clarified extensively. Topics in this field including recent advances will be discussed.

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Item Type:	Proceedings Paper
AGROVOC Term:	ANIMAL BIOTECHNOLOGY
AGROVOC Term:	LIVESTOCK
AGROVOC Term:	OVARIAN FOLLICLES
AGROVOC Term:	OVA
AGROVOC Term:	OVARIAN FOLLICLES
AGROVOC Term:	OOGENESIS
AGROVOC Term:	BIOLOGICAL DEVELOPMENT
AGROVOC Term:	JAPAN
Geographical Term:	MALAYSIA
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:27
URI:	http://webagris.upm.edu.my/id/eprint/16457

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