The 'non-allergenicity' of NR dry rubber products with reference to type 1 protein allergy

Esah Yip, . and Turjanmaa Kristiina, . and Makinen Kiljunen Soili, . The 'non-allergenicity' of NR dry rubber products with reference to type 1 protein allergy. pp. 48-52.

The protein allergy issue associated with some natural rubber latex-dipped medical devices has caused certain concern over the use of NR dry rubber products. A study was therefore carried out to evaluate a number of the commercially available dry rubber grades both raw and vulcanized and some dry rubber products. Their extractable protein contents shown to be related to the allergenicity of the products were measured by the RRIM modified Lowry method while their allergen activities if any were assessed by both the skin-prick test and the RAST-inhibition test. Results revealed that NR dry rubbers and dry rubber products have not only extremely low extractable protein contents (often less than 20 micro g per g) but also very low or negligible allergenicity. Hence it may be concluded that dry rubbers and dry rubber products are generally not affected by the protein allergy problem.

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Abstract

The protein allergy issue associated with some natural rubber latex-dipped medical devices has caused certain concern over the use of NR dry rubber products. A study was therefore carried out to evaluate a number of the commercially available dry rubber grades both raw and vulcanized and some dry rubber products. Their extractable protein contents shown to be related to the allergenicity of the products were measured by the RRIM modified Lowry method while their allergen activities if any were assessed by both the skin-prick test and the RAST-inhibition test. Results revealed that NR dry rubbers and dry rubber products have not only extremely low extractable protein contents (often less than 20 micro g per g) but also very low or negligible allergenicity. Hence it may be concluded that dry rubbers and dry rubber products are generally not affected by the protein allergy problem.

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Item Type:	Article
Additional Information:	Summary (En)
AGROVOC Term:	CAUCHO
AGROVOC Term:	PRODUCTOS
AGROVOC Term:	REACCIONES ALERGICAS
AGROVOC Term:	CONTENIDO PROTEICO
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:51
URI:	http://webagris.upm.edu.my/id/eprint/17219

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