Toxicity and palatability of scilliroside rodenticides to Rattus argentiventer rats

Lam Y.M., . Toxicity and palatability of scilliroside rodenticides to Rattus argentiventer rats. pp. 113-120. ISSN 0128-0686

Scilliroside was evaluated against Rattus argentiventer in the laboratory. The median lethal doses (LD50) of scilliroside against R. argentiventer was 0.64 mg/kg and the LD99 was 2.2l mg/kg. Corrected mean days to death in rats succumbing to a lethal dose by gavage were 2.3 (SE 0.3) days in males and 1.8 (SE 0.2) days in females. Scilliroside at all the concentrations tested did not elicite 100 mortality in both sexes in 1-day no-choice tests as a result of poor bait consumption. The lowest lethal dose was 0.06 mg/kg and the highest dose survived was 1.21 mg/kg in males. In females the lowest lethal dose was 0.10 mg/kg and the highest dose survived was 0.46 mg/kg. Corrected mean days to death in rats succumbing to a lethal dose in no-choice feeding tests were 2.0 (SE 0.6) days in males and 2.5 (SE 0.7) days in females. Palatability studies (4-day choice feeding tests) indicated that scilliroside at all the concentrations tested showed poor palatability against R. argentiventer giving low mortality for both sexes as a result of poor consumption of the poison baits. Rats were able to detect scilliroside at the lowest concentration tested (0.01) resulting in very poor bait consumption

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Abstract

Scilliroside was evaluated against Rattus argentiventer in the laboratory. The median lethal doses (LD50) of scilliroside against R. argentiventer was 0.64 mg/kg and the LD99 was 2.2l mg/kg. Corrected mean days to death in rats succumbing to a lethal dose by gavage were 2.3 (SE 0.3) days in males and 1.8 (SE 0.2) days in females. Scilliroside at all the concentrations tested did not elicite 100 mortality in both sexes in 1-day no-choice tests as a result of poor bait consumption. The lowest lethal dose was 0.06 mg/kg and the highest dose survived was 1.21 mg/kg in males. In females the lowest lethal dose was 0.10 mg/kg and the highest dose survived was 0.46 mg/kg. Corrected mean days to death in rats succumbing to a lethal dose in no-choice feeding tests were 2.0 (SE 0.6) days in males and 2.5 (SE 0.7) days in females. Palatability studies (4-day choice feeding tests) indicated that scilliroside at all the concentrations tested showed poor palatability against R. argentiventer giving low mortality for both sexes as a result of poor consumption of the poison baits. Rats were able to detect scilliroside at the lowest concentration tested (0.01) resulting in very poor bait consumption

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Item Type:	Article
Additional Information:	Summaries (En Ms)
AGROVOC Term:	ALIMENTACION DE LOS ANIMALES
AGROVOC Term:	RODENTICIDAS
AGROVOC Term:	TOXICIDAD
AGROVOC Term:	PROPIEDADES ORGANOLEPTICAS
AGROVOC Term:	RATA
AGROVOC Term:	MORTALIDAD
Depositing User:	Ms. Norfaezah Khomsan
Last Modified:	24 Apr 2025 05:57
URI:	http://webagris.upm.edu.my/id/eprint/20985

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