Antioxidant and -glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants

Mediani A., . and Lee S. Y., . and Azliana A. B. S., . and Abas F., . and Nur Ashikin A. H., . Antioxidant and -glucosidase inhibitory activities of the leaf and stem of selected traditional medicinal plants. pp. 165-172. ISSN 22317546

The study was aimed to determine the antioxidant and -glucosidase inhibition activities of the stem and leaf of five different traditional medicinal plants. The studied plants exhibited varied antioxidant and -glucosidase inhibition activities. The antioxidant activities of the plants were determined through their free radical scavenging capabilities using DPPH assay. The most potent antioxidant activity was demonstrated by Neptunia oleracea with an IC50 of 35.45 and 29.72 g/mL for leaf and stem respectively. For -glucosidase inhibition activity Neptunia oleracea exhibited potential -glucosidase inhibition activity with IC50 value of 19.09 and 19.74 g/mL for leaf and stem respectively. The highest total phenolic content (TPC) was also marked in Neptunia oleracea leaf and stem with value of 40.88 and 21.21 mg GAE/g dry weight respectively. The results also showed that Strobilanthes crispus collected from two different locations possessed different levels of phenolic content antioxidant and -glucosidase inhibition activities. The study revealed that phenolic compounds could be the main contributors to the antioxidant and -glucosidase inhibition activities with R values of 78.9 and 67.4 respectively. In addition antioxidant and -glucosidase were positively correlated (R 81.9). Neptunia oleracea could be suggested as a potential natural source of antioxidant and antidiabetic compounds that can be used for the prevention or treatment of diabetes.

Full text available from: Official URL: http://ifrj.upm.edu.my/21%20(01)%202014/24%20IFRJ%...

Abstract

The study was aimed to determine the antioxidant and -glucosidase inhibition activities of the stem and leaf of five different traditional medicinal plants. The studied plants exhibited varied antioxidant and -glucosidase inhibition activities. The antioxidant activities of the plants were determined through their free radical scavenging capabilities using DPPH assay. The most potent antioxidant activity was demonstrated by Neptunia oleracea with an IC50 of 35.45 and 29.72 g/mL for leaf and stem respectively. For -glucosidase inhibition activity Neptunia oleracea exhibited potential -glucosidase inhibition activity with IC50 value of 19.09 and 19.74 g/mL for leaf and stem respectively. The highest total phenolic content (TPC) was also marked in Neptunia oleracea leaf and stem with value of 40.88 and 21.21 mg GAE/g dry weight respectively. The results also showed that Strobilanthes crispus collected from two different locations possessed different levels of phenolic content antioxidant and -glucosidase inhibition activities. The study revealed that phenolic compounds could be the main contributors to the antioxidant and -glucosidase inhibition activities with R values of 78.9 and 67.4 respectively. In addition antioxidant and -glucosidase were positively correlated (R 81.9). Neptunia oleracea could be suggested as a potential natural source of antioxidant and antidiabetic compounds that can be used for the prevention or treatment of diabetes.

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Item Type:	Article
AGROVOC Term:	Natural antioxidants
AGROVOC Term:	Alpha glucosidase
AGROVOC Term:	Inhibition
AGROVOC Term:	Leaf
AGROVOC Term:	Stems
AGROVOC Term:	Medicinal plants
AGROVOC Term:	Free radicals
AGROVOC Term:	Fabaceae
AGROVOC Term:	Phenolic content
AGROVOC Term:	Acanthaceae
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:26
URI:	http://webagris.upm.edu.my/id/eprint/21271

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