Citation
Siti Syarifah M. M., . and Asiah O., . and Norhayati I., . and Nurhanan M. Y., . and Mohd Ilham M. A., . and Lili Sahira H., . Anti-proliferative activities of 32 Malaysian plant species in breast cancer cell lines. pp. 77-81. ISSN 0128-1283
Abstract
Anti-proliferative activities of 143 crude extracts obtained from 32 plants collected from the rain forests of Pahang Malaysia were evaluated in two breast cancer cell lines i.e. MCF-7 and T47D obtained from the American Type Culture Collection USA. The objective of this study was to bioprospect a list of plants to find out their potential to be developed into anti-cancer drug(s) by means of bioassay guided isolation procedure. Mter performing sulforhodamine-B assay 13 crude extracts from 11 plant species were found to have active anti-proliferative effects (IC50 s 100 llg mJ-l).
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Abstract
Anti-proliferative activities of 143 crude extracts obtained from 32 plants collected from the rain forests of Pahang Malaysia were evaluated in two breast cancer cell lines i.e. MCF-7 and T47D obtained from the American Type Culture Collection USA. The objective of this study was to bioprospect a list of plants to find out their potential to be developed into anti-cancer drug(s) by means of bioassay guided isolation procedure. Mter performing sulforhodamine-B assay 13 crude extracts from 11 plant species were found to have active anti-proliferative effects (IC50 s 100 llg mJ-l).
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Rain forests |
| AGROVOC Term: | bioprospecting |
| AGROVOC Term: | Bioassays |
| AGROVOC Term: | Cancer (disease) |
| AGROVOC Term: | Botanists |
| AGROVOC Term: | Plant extracts |
| AGROVOC Term: | Methanol |
| AGROVOC Term: | Evaporators |
| AGROVOC Term: | Incubators |
| AGROVOC Term: | Fractionation |
| Geographical Term: | Malaysia |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 26 Apr 2025 15:32 |
| URI: | http://webagris.upm.edu.my/id/eprint/21726 |
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