Antioxidant and antihemolytic activities of common Nilgiri barberry (Berberis tinctoria Lesch.) from south India

Smilin A. G., . and Maheshu V., . and Gincy M. M., . and Joji C., . and Sasikumar J. M., . Antioxidant and antihemolytic activities of common Nilgiri barberry (Berberis tinctoria Lesch.) from south India. pp. 1601-1607. ISSN 2231-7546

In this study the potential of Common Nilgiri Barberry (Berberis tinctoria Lesch.) fruits as nutraceutical/functional food polyphenolic contents and the in vitro antioxidant and antihemolytic activity were determined. The phenolic content (TP) of the fresh fruits is 410 0.082 mg gallic acid equivalents (GAE)/100g and total flavonoid content (TF) is 320 0.120 mg quercetin equivalents (QE)/100g. The methanol extract exhibited scavenging capacity towards 1 1 “ diphenyl “ 2- picryl hydrozyl (DPPH) superoxide anion hydroxyl ion radicals and nitric oxide. The TEAC of fruit extract ranged from 1.063-2.364 mM TE/g. The extract also exerted strong reducing capacity and had strong Fe3 chelation (EC50 45.24 1.42 g mL-1) and remarkable reduction of erythrocyte hemolysis (EC50 71.1 0.22 g ml-1). Positive correlations were observed between polyphenolic contents and the antioxidant capacities. In conclusion the Barberry fruit from India endowed with polyphenols could be a potential source of for the development of natural antioxidants/nutraceuticals.

Full text available from: Official URL: http://www.ifrj.upm.edu.my/19%20(04)%202012/42%20I...

Abstract

In this study the potential of Common Nilgiri Barberry (Berberis tinctoria Lesch.) fruits as nutraceutical/functional food polyphenolic contents and the in vitro antioxidant and antihemolytic activity were determined. The phenolic content (TP) of the fresh fruits is 410 0.082 mg gallic acid equivalents (GAE)/100g and total flavonoid content (TF) is 320 0.120 mg quercetin equivalents (QE)/100g. The methanol extract exhibited scavenging capacity towards 1 1 “ diphenyl “ 2- picryl hydrozyl (DPPH) superoxide anion hydroxyl ion radicals and nitric oxide. The TEAC of fruit extract ranged from 1.063-2.364 mM TE/g. The extract also exerted strong reducing capacity and had strong Fe3 chelation (EC50 45.24 1.42 g mL-1) and remarkable reduction of erythrocyte hemolysis (EC50 71.1 0.22 g ml-1). Positive correlations were observed between polyphenolic contents and the antioxidant capacities. In conclusion the Barberry fruit from India endowed with polyphenols could be a potential source of for the development of natural antioxidants/nutraceuticals.

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Item Type:	Article
AGROVOC Term:	Antioxidants
AGROVOC Term:	Polyphenol content
AGROVOC Term:	Epidemiological surveys
AGROVOC Term:	Vitamins
AGROVOC Term:	Flavonoids
AGROVOC Term:	Carotenoids
AGROVOC Term:	Berberidaceae
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:27
URI:	http://webagris.upm.edu.my/id/eprint/22255

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