Total anthocyanins chlorogenic acid concentration antioxidant and in ovo anti-angiogenic activities of rabbiteye blueberries

Vuthijumnonk J., . and Heyes J. A., . and Molan A. L., . Total anthocyanins chlorogenic acid concentration antioxidant and in ovo anti-angiogenic activities of rabbiteye blueberries. pp. 515-520. ISSN 2231-7546

Anthocyanins are the most abundant phytochemicals found in blueberries and exhibit several biological properties including antioxidant activity. This study investigated total anthocyanin concentration chlorogenic acid concentration antioxidant activity using FRAP assay and anti-angiogenic activity of five rabbiteye blueberry varieties (Centurion Maru Rahi Ono Tifblue). Tifblue showed the highest total anthocyanin and chlorogenic acid concentrations while Rahi contained the lowest. Interestingly antioxidant activity was better correlated with chlorogenic acid concentration than anthocyanin. Anti-angiogenic properties of blueberry extracts were determined by chicken chorioallantoic membrane (CAM) assay. Blueberry extracts had macroscopic effects on CAM which were measured both quantitatively and qualitatively. In control CAM a blood vessel network was formed with fine capillaries while there were fewer shorter more branched capillaries in blueberry extract treated CAMs. Even though some blood vessels or capillaries in the blueberry-treated CAMs were elongated the vessels largely failed to interconnect to form a network. Three varieties Centurion Maru and Tifblue had the strongest anti-angiogenic impact. The best correlation between composition and anti-angiogenic activity was found with anthocyanin concentration rather than antioxidant activity. Blueberries contain various phytochemicals which contribute to their high antioxidant activity. It is well accepted that berry antioxidant activity plays an important role in the prevention of several diseases. However this study demonstrated that blueberries exhibited other biological activity that is not necessarily related to their antioxidant activity but may have a role in disease prevention. Moreover different phytochemicals are responsible for different biological activities.

Full text available from: Official URL: http://www.ifrj.upm.edu.my/23%20(02)%202016/(9).pd...

Abstract

Anthocyanins are the most abundant phytochemicals found in blueberries and exhibit several biological properties including antioxidant activity. This study investigated total anthocyanin concentration chlorogenic acid concentration antioxidant activity using FRAP assay and anti-angiogenic activity of five rabbiteye blueberry varieties (Centurion Maru Rahi Ono Tifblue). Tifblue showed the highest total anthocyanin and chlorogenic acid concentrations while Rahi contained the lowest. Interestingly antioxidant activity was better correlated with chlorogenic acid concentration than anthocyanin. Anti-angiogenic properties of blueberry extracts were determined by chicken chorioallantoic membrane (CAM) assay. Blueberry extracts had macroscopic effects on CAM which were measured both quantitatively and qualitatively. In control CAM a blood vessel network was formed with fine capillaries while there were fewer shorter more branched capillaries in blueberry extract treated CAMs. Even though some blood vessels or capillaries in the blueberry-treated CAMs were elongated the vessels largely failed to interconnect to form a network. Three varieties Centurion Maru and Tifblue had the strongest anti-angiogenic impact. The best correlation between composition and anti-angiogenic activity was found with anthocyanin concentration rather than antioxidant activity. Blueberries contain various phytochemicals which contribute to their high antioxidant activity. It is well accepted that berry antioxidant activity plays an important role in the prevention of several diseases. However this study demonstrated that blueberries exhibited other biological activity that is not necessarily related to their antioxidant activity but may have a role in disease prevention. Moreover different phytochemicals are responsible for different biological activities.

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Item Type:	Article
AGROVOC Term:	Rabbiteye blueberries
AGROVOC Term:	Extraction
AGROVOC Term:	Anthocyanins
AGROVOC Term:	Chlorogenic acid
AGROVOC Term:	Antioxidants
AGROVOC Term:	Blood vessels
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:27
URI:	http://webagris.upm.edu.my/id/eprint/22529

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