Germinated-soy milk in supressing inflammation and oxidative stress in blood plasma and breast milk of lactating mothers

Winarsi H., . and Sasongko N. D., . and Purwanto A., . Germinated-soy milk in supressing inflammation and oxidative stress in blood plasma and breast milk of lactating mothers. pp. 646-652. ISSN 2231-7546

Current study aimed to determine the potency of germinated-soy milk (GSM) on Superoxide Dismutase (SOD) activity and Malondialdehyde (MDA) and C-Reactive Protein (C-RP) levels in the blood plasma and skim milk of lactating mothers. Subjects were 50 lactating mothers 20-35 years old having newborns up to 6 months old and willing to sign informed consent. Subjects were divided into two groups consisting of 25 women. Group I was treated with GSM while group II was given placebo for two consecutive months. Samples of blood plasma and mothers breast milk were taken 3 times at different times: 0 1 and 2 months after intervention. Blood samples were taken intravenously using venoject tubes containing EDTA. The blood plasma and skim milk were used as test samples for activities of SOD as well as the MDA and C-RP levels. Differences were considered significant at P0.05. Results GSM increased SOD activity in the blood plasma (P 0.043) and also in skim milk (P 0.56). On the other hand level of MDA decreased in the blood plasma (P 9.65E-06) and in skim milk (P 0.047) and also the CRP reduced in the blood plasma (P 0.0015) and in skim milk (P 0.77). GSM could be used to reduce oxidative stress and suppress inflammatory levels of lactating mothers.

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Abstract

Current study aimed to determine the potency of germinated-soy milk (GSM) on Superoxide Dismutase (SOD) activity and Malondialdehyde (MDA) and C-Reactive Protein (C-RP) levels in the blood plasma and skim milk of lactating mothers. Subjects were 50 lactating mothers 20-35 years old having newborns up to 6 months old and willing to sign informed consent. Subjects were divided into two groups consisting of 25 women. Group I was treated with GSM while group II was given placebo for two consecutive months. Samples of blood plasma and mothers breast milk were taken 3 times at different times: 0 1 and 2 months after intervention. Blood samples were taken intravenously using venoject tubes containing EDTA. The blood plasma and skim milk were used as test samples for activities of SOD as well as the MDA and C-RP levels. Differences were considered significant at P0.05. Results GSM increased SOD activity in the blood plasma (P 0.043) and also in skim milk (P 0.56). On the other hand level of MDA decreased in the blood plasma (P 9.65E-06) and in skim milk (P 0.047) and also the CRP reduced in the blood plasma (P 0.0015) and in skim milk (P 0.77). GSM could be used to reduce oxidative stress and suppress inflammatory levels of lactating mothers.

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Item Type:	Article
AGROVOC Term:	Soy milk
AGROVOC Term:	Germination
AGROVOC Term:	Inflammation
AGROVOC Term:	Oxidative stress
AGROVOC Term:	Blood plasma
AGROVOC Term:	Superoxide dismutase
AGROVOC Term:	malondialdehyde
AGROVOC Term:	Indonesia
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:27
URI:	http://webagris.upm.edu.my/id/eprint/22591

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