Citation
Khin M. N., . and M. Zamri Saad, . and M. M. Noordin, . Pathological changes in the lungs of calves following intratracheal exposure to Pasteurella multocida B:2. pp. 113-117. ISSN 1511-3701
Abstract
Pasteurella multocida B:2 is an etiological agent of hemorrhagic septicemia in cattle and buffaloes. It is commonly fatal and considered as one of the most economically important cattle diseases in Southeast Asia. This study describes the pathological changes in the lungs of calves following intra-tracheal challenge with wild-type P.multocida B:2. For this purpose six calves of 8-month old were selected and divided into two groups of 3 calves. Calves of Group 1 were challenged with intra-tracheal 5ml inoculum containing 109 cfu/ml of wild-type P. multocida B:2 while the calves of Group 2 were similarly administered with PBS. All the challenged calves of Group 1 showed slight dullness and were found to be inactive within 72 hours after inoculation but none died. Meanwhile their lungs showed petechiations and patches of acute pneumonia affecting few lobules. Histological examinations revealed the presence of haemorrhages into the alveoli whereas some sections showed thickened inter-alveolar septa due to congestion and the presence of neutrophils. However pulmonary oedema was absent. P.multocida B:2 was successfully isolated from all the calves of Group 1.
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Abstract
Pasteurella multocida B:2 is an etiological agent of hemorrhagic septicemia in cattle and buffaloes. It is commonly fatal and considered as one of the most economically important cattle diseases in Southeast Asia. This study describes the pathological changes in the lungs of calves following intra-tracheal challenge with wild-type P.multocida B:2. For this purpose six calves of 8-month old were selected and divided into two groups of 3 calves. Calves of Group 1 were challenged with intra-tracheal 5ml inoculum containing 109 cfu/ml of wild-type P. multocida B:2 while the calves of Group 2 were similarly administered with PBS. All the challenged calves of Group 1 showed slight dullness and were found to be inactive within 72 hours after inoculation but none died. Meanwhile their lungs showed petechiations and patches of acute pneumonia affecting few lobules. Histological examinations revealed the presence of haemorrhages into the alveoli whereas some sections showed thickened inter-alveolar septa due to congestion and the presence of neutrophils. However pulmonary oedema was absent. P.multocida B:2 was successfully isolated from all the calves of Group 1.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Calves |
| AGROVOC Term: | Lungs |
| AGROVOC Term: | Pathology |
| AGROVOC Term: | Pasteurella multocida |
| AGROVOC Term: | Experiments |
| AGROVOC Term: | Bacteria |
| AGROVOC Term: | Isolation |
| AGROVOC Term: | Lesions |
| AGROVOC Term: | Pneumonia |
| AGROVOC Term: | Pulmonary diseases |
| Geographical Term: | Malaysia |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 28 Apr 2025 00:09 |
| URI: | http://webagris.upm.edu.my/id/eprint/22781 |
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