Citation
Tang J. L. K., . and Nyam K. L., . and Long K., . Anti-ulcer activity of Hibiscus cannabinus and Hibiscus sabdariffa seeds in ulcer-induced rats. pp. 1164-1172. ISSN 2231-7546
Abstract
The aim of this research is to determine the antiulcer properties and percentage protection of Hibiscus cannabinus and Hibiscus sabdariffa seed samples towards ulcer-induced Sprague dawley rats. Rats were divided into six groups each for each ulceration method and fed with distilled water Omeprazole H. cannabinus seed oil (HCSO) H. cannabinus seed extract (HCSE) H. sabdariffa seed oil (HSSO) and H. sabdariffa seed extract (HSSE) respectively via oral administration. Among the two plants tested H. cannabinus showed the best protection percentage towards ethanol non-steroidal anti-inflammatory drugs (NSAIDs) and cold restrain stress induced ulcers. H. cannabinus seed extract (HSSE) exhibited an exceptionally high ulcer protection of 74.98 0.78 against NSAIDs induced ulcer. The gastric lesions were controlled primarily by both mucosal protection and acid inhibition. In conclusion addition of these seeds to the daily diet may reduce free radical activity in the body and reduce the risk of developing peptic ulcer disease.
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Abstract
The aim of this research is to determine the antiulcer properties and percentage protection of Hibiscus cannabinus and Hibiscus sabdariffa seed samples towards ulcer-induced Sprague dawley rats. Rats were divided into six groups each for each ulceration method and fed with distilled water Omeprazole H. cannabinus seed oil (HCSO) H. cannabinus seed extract (HCSE) H. sabdariffa seed oil (HSSO) and H. sabdariffa seed extract (HSSE) respectively via oral administration. Among the two plants tested H. cannabinus showed the best protection percentage towards ethanol non-steroidal anti-inflammatory drugs (NSAIDs) and cold restrain stress induced ulcers. H. cannabinus seed extract (HSSE) exhibited an exceptionally high ulcer protection of 74.98 0.78 against NSAIDs induced ulcer. The gastric lesions were controlled primarily by both mucosal protection and acid inhibition. In conclusion addition of these seeds to the daily diet may reduce free radical activity in the body and reduce the risk of developing peptic ulcer disease.
Additional Metadata
| Item Type: | Article |
|---|---|
| AGROVOC Term: | Hibiscus cannabinus |
| AGROVOC Term: | Hibiscus sabdariffa |
| AGROVOC Term: | Stomach ulcer |
| AGROVOC Term: | Distilled water |
| AGROVOC Term: | Extracts |
| AGROVOC Term: | Oilseeds |
| AGROVOC Term: | Antiinflammatory agents |
| AGROVOC Term: | Seed extracts |
| AGROVOC Term: | Mucosal diseases |
| AGROVOC Term: | Ethanol |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 06:27 |
| URI: | http://webagris.upm.edu.my/id/eprint/22787 |
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