Minimising chemical hazards to improve biocompatibility of natural rubber latex products

Siti Nor Qamarina M., . and Tajul Anuar Y., . and Nur Fadilah R., . and Mok K. L., . Minimising chemical hazards to improve biocompatibility of natural rubber latex products. pp. 240-256. ISSN 1511-1768

This study examines the residual rubber chemicals commonly used in natural rubber (NR) latex formulation and their effects on the biocompatibility of finished products. Several in-house compounds differing in chemical compositions were prepared and analysed for their physical properties residual chemicals and biocompatibility. From this an optimum formulation with low residual chemical content and acceptable physical properties was selected as a model design. In vitro cytotoxicity elution tests with L 929 fibroblasts showed all sample extracts to be poorly biocompatible.

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Abstract

This study examines the residual rubber chemicals commonly used in natural rubber (NR) latex formulation and their effects on the biocompatibility of finished products. Several in-house compounds differing in chemical compositions were prepared and analysed for their physical properties residual chemicals and biocompatibility. From this an optimum formulation with low residual chemical content and acceptable physical properties was selected as a model design. In vitro cytotoxicity elution tests with L 929 fibroblasts showed all sample extracts to be poorly biocompatible.

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Item Type:	Article
AGROVOC Term:	Natural rubber
AGROVOC Term:	Latex
AGROVOC Term:	Chemical engineering
AGROVOC Term:	Residual effects
AGROVOC Term:	Physical properties
AGROVOC Term:	Health risks
AGROVOC Term:	Tensile strength
AGROVOC Term:	Cytotoxicity
Geographical Term:	Malaysia
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	28 Apr 2025 03:09
URI:	http://webagris.upm.edu.my/id/eprint/23037

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