Impermeability of gloves and differently formulated NR latex films to phiX174


Citation

Hasma H., . and Lytle C. D., . Impermeability of gloves and differently formulated NR latex films to phiX174. pp. 209-221. ISSN 1511-1768

Abstract

The permeability of gloves and differently formulated NR latex films to a challenge surrogate virus fX174 of diameter 27 nm was assessed by a newly-developed method which could detect holes greater than or equal to 2 urn. Samples from chlorinated and copolymerised natural rubber gloves and gloves with different extractable protein contents were found to be impermeable to the virus even when stretched 9x their original areas. Similar results were obtained with samples from nitrile and vinyl gloves. The integrities of the latex films were not affected when the films were of different high-ammoniated latex concentrate sources different levels of non-rubber constituents different curing systems different moduli or different leaching protocols. The films maintained their barrier properties even after being aged at 70C for 7 or 14 days. These clearly showed that stretched latex films were not porous. Furthermore impermeability to a small virus such as fX174 indicated that the films could also be impervious to human viruses such as hepatitis B or C viruses human immunodeficiency virus herpes simplex virus and cytomegalovirus which are up to five times bigger than fX174.


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Abstract

The permeability of gloves and differently formulated NR latex films to a challenge surrogate virus fX174 of diameter 27 nm was assessed by a newly-developed method which could detect holes greater than or equal to 2 urn. Samples from chlorinated and copolymerised natural rubber gloves and gloves with different extractable protein contents were found to be impermeable to the virus even when stretched 9x their original areas. Similar results were obtained with samples from nitrile and vinyl gloves. The integrities of the latex films were not affected when the films were of different high-ammoniated latex concentrate sources different levels of non-rubber constituents different curing systems different moduli or different leaching protocols. The films maintained their barrier properties even after being aged at 70C for 7 or 14 days. These clearly showed that stretched latex films were not porous. Furthermore impermeability to a small virus such as fX174 indicated that the films could also be impervious to human viruses such as hepatitis B or C viruses human immunodeficiency virus herpes simplex virus and cytomegalovirus which are up to five times bigger than fX174.

Additional Metadata

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Item Type: Article
AGROVOC Term: Natural rubber
AGROVOC Term: Latex
AGROVOC Term: Formulations
AGROVOC Term: Porosity
AGROVOC Term: Leaching
AGROVOC Term: Bacteriophages
AGROVOC Term: Ageing
AGROVOC Term: Permeation
AGROVOC Term: Cross-linking
AGROVOC Term: Protein content
Geographical Term: Malaysia
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 28 Apr 2025 03:30
URI: http://webagris.upm.edu.my/id/eprint/23326

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