Immunoassays for determination of antigens and allergens in latex products


Citation

Cardosa M. J., . and Samuel-Verghese S., . and Sharifah Hamid, . and Yeang H. Y., . Immunoassays for determination of antigens and allergens in latex products. pp. 63-69. ISSN 0127-7065

Abstract

The quality control of latex products used in the medical setting has to take into account the presence of allergens which induce a Type I hyper sensitivity response. Assays to measure the total protein eluted from these products does not address the problem of allergenicity of the proteins extracted. This paper introduces to rubber manufacturers the concept of enzyme irrmunoassay and describes various immunoassay formats by which antigens can be detected. The paper further describes a number of examples which show that gloves produced by different manufacturers contain different amounts of antigens and monoclonal antibodies are used to show that different antigens are found in different gloves.


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Abstract

The quality control of latex products used in the medical setting has to take into account the presence of allergens which induce a Type I hyper sensitivity response. Assays to measure the total protein eluted from these products does not address the problem of allergenicity of the proteins extracted. This paper introduces to rubber manufacturers the concept of enzyme irrmunoassay and describes various immunoassay formats by which antigens can be detected. The paper further describes a number of examples which show that gloves produced by different manufacturers contain different amounts of antigens and monoclonal antibodies are used to show that different antigens are found in different gloves.

Additional Metadata

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Item Type: Article
AGROVOC Term: Rubber industry
AGROVOC Term: Latex
AGROVOC Term: Immunoassay
AGROVOC Term: Antigens
AGROVOC Term: Allergens
AGROVOC Term: Quality controls
AGROVOC Term: Hypersensitivity
AGROVOC Term: Manufactured products
AGROVOC Term: Antibodies
AGROVOC Term: Indirect ELISA
Geographical Term: Malaysia
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 28 Apr 2025 03:58
URI: http://webagris.upm.edu.my/id/eprint/23405

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