Citation
Patil A. R., . and Mahamuni P. P., . and Ghosh J. S., . Proteolytic and lipolytic properties of endotoxins (enterotoxins) produced by Salmonella typhi NCIM 5255 Salmonella typhimurium NCIM 2501 and Shigella flexneri NCIM 5265. pp. 2685-2688. ISSN 2231-7546
Abstract
Endotoxin is a major component of the outer membrane (OM) of Gram-negative bacteria. It was observed that endotoxin plays an important role in the pathogenicity of Gram-negative bacterial infections. In humans it is a potent mediator of a broad range of patho-physiological effects mostly in the gasterointestinal tracts. Hence these are also referred as enterotoxins. These toxic activities like lethal toxicity pyrogenicity and tissue-necrotizing activity as well as many beneficial ones related to immunostimulation. This investigation involve the extraction of endotoxins from Salmonella typhimurium NCIM 2501 Salmonella typhi NCIM 5255 Shigella flexnerii NCIM 5265. Highest amount 23mg/mL) of endotoxin was obtained from Salmonella typhimurium. Further the extracted endotoxin was used to check antibacterial activity on other bacteria which showed good antibacterial activity against Bacillus subtilis.It also showed caseinase and lecithinase activity. Endotoxin extracted from Salmonella typhimurium had caseinase and lecithinase activity more as compared to that of Salmonella typhi Shigella flexnerii.
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Abstract
Endotoxin is a major component of the outer membrane (OM) of Gram-negative bacteria. It was observed that endotoxin plays an important role in the pathogenicity of Gram-negative bacterial infections. In humans it is a potent mediator of a broad range of patho-physiological effects mostly in the gasterointestinal tracts. Hence these are also referred as enterotoxins. These toxic activities like lethal toxicity pyrogenicity and tissue-necrotizing activity as well as many beneficial ones related to immunostimulation. This investigation involve the extraction of endotoxins from Salmonella typhimurium NCIM 2501 Salmonella typhi NCIM 5255 Shigella flexnerii NCIM 5265. Highest amount 23mg/mL) of endotoxin was obtained from Salmonella typhimurium. Further the extracted endotoxin was used to check antibacterial activity on other bacteria which showed good antibacterial activity against Bacillus subtilis.It also showed caseinase and lecithinase activity. Endotoxin extracted from Salmonella typhimurium had caseinase and lecithinase activity more as compared to that of Salmonella typhi Shigella flexnerii.
Additional Metadata
Item Type: | Article |
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AGROVOC Term: | Endotoxins |
AGROVOC Term: | Salmonella |
AGROVOC Term: | Salmonella typhimurium |
AGROVOC Term: | Shigella |
AGROVOC Term: | Bacillus subtilis |
AGROVOC Term: | Micrococcus |
AGROVOC Term: | Gram negative bacteria |
AGROVOC Term: | Antibacterial agents |
AGROVOC Term: | Antibacterial properties |
AGROVOC Term: | Bacterial diseases |
Depositing User: | Ms. Suzila Mohamad Kasim |
Last Modified: | 24 Apr 2025 06:28 |
URI: | http://webagris.upm.edu.my/id/eprint/23935 |
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