Comparative assessment of antioxidant activities in Aquilaria malaccensis leaf extracts

Zalilawati Mat Rashid, . and Amella J. Johar, . and Abdul Manaf Ali, . and Mahmod N.H., . and Mohd Haziq Abdul Hamid, . Comparative assessment of antioxidant activities in Aquilaria malaccensis leaf extracts. pp. 77-85. ISSN 2180-1983

We examined antioxidant activities of Aquilaria malaccensis leaves which is a by-product that is normally discarded during cultivation. Crude leaf extracts were obtained from hot extraction by solvents of different polarities; distilled water ethanol and chloroform. The antioxidant activities of respective crude extract were tested and compared between extraction solvents used using DPPH free radical scavenging activity ferric-reducing antioxidant power (FRAP) assay hydrogen peroxide (H2O2) scavenging assay superoxide (SOD) scavenging activity assay and nitric oxide (NO) scavenging assay. Except for SOD assay the highest percentage of inhibitions and the lowest IC50 values were achieved in alcohol-based leaf extract. In conclusion the crude extract of Aquilaria malaccensis possess a considerable antioxidant activities regardless of extracting solvents used but the highest was found using ethanol. The activities demonstrated against the various oxidants tested will help to target disease related to the specific oxidants causing it.

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Abstract

We examined antioxidant activities of Aquilaria malaccensis leaves which is a by-product that is normally discarded during cultivation. Crude leaf extracts were obtained from hot extraction by solvents of different polarities; distilled water ethanol and chloroform. The antioxidant activities of respective crude extract were tested and compared between extraction solvents used using DPPH free radical scavenging activity ferric-reducing antioxidant power (FRAP) assay hydrogen peroxide (H2O2) scavenging assay superoxide (SOD) scavenging activity assay and nitric oxide (NO) scavenging assay. Except for SOD assay the highest percentage of inhibitions and the lowest IC50 values were achieved in alcohol-based leaf extract. In conclusion the crude extract of Aquilaria malaccensis possess a considerable antioxidant activities regardless of extracting solvents used but the highest was found using ethanol. The activities demonstrated against the various oxidants tested will help to target disease related to the specific oxidants causing it.

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Item Type:	Article
AGROVOC Term:	Thymelaeaceae
AGROVOC Term:	Antioxidants
AGROVOC Term:	Leaves
AGROVOC Term:	Leaf extracts
AGROVOC Term:	Extraction
AGROVOC Term:	Distilled water
AGROVOC Term:	Ethanol
AGROVOC Term:	Chloroform
AGROVOC Term:	Solvents
AGROVOC Term:	Inhibition
Geographical Term:	Malaysia
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	28 Apr 2025 06:04
URI:	http://webagris.upm.edu.my/id/eprint/24073

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