Partition coefficient water solubility and aquatic toxicity of short-chain palm fatty acids

Siti Afida Ishak, . and Razmah Ghazali, . Partition coefficient water solubility and aquatic toxicity of short-chain palm fatty acids. pp. 75-81. ISSN 1511-2780

The octanol/water partition coefficient (Pow) and water solubility (Sw) are important physico-chemical properties for an environmental risk assessment of a chemical substance as well as ecotoxicity. It can be an indication of the extent to which the chemical might bioaccumulate in aquatic organisms. The log Pow of palm-based fatty acids was estimated using high performance liquid chromatography (HPLC) method while the Sw value was determined using linear correlation between Sw and log Pow of reference compounds. The ecotoxicity of palm-based fatty acids was measured using test method OECD 203 Fish Acute Toxicity with common carp (Cyprinos carpio) as the test species. The short-chained C6 to C10 palm fatty acids were chosen for this study because they are generally toxic and can cause irritation to human and may have an adverse effect towards aquatic organisms. The log Pow values showed that both C6 and C8 fatty acids had low affinity towards aquatic organisms but C10 fatty acid showed medium affinity towards these organisms. As for water solubility C6 fatty acid had high affinity towards water while both C8 and C10 fatty acids showed medium affinity towards water. The LC50 value of C6 C8 and C10 palm FAs are 7 mg litre-1 7 mg litre-1 and 20 mg litre-1 respectively. It can be concluded that the higher the carbon chain number of the fatty acid the higher is the partition coefficient value the water solubility decreases. The palm-based fatty acid can be considered as moderately toxic to aquatic organisms. These data can be used by the palm-based oleochemical manufacturers for product registration preparation of product dossier or for marketing purposes.

Full text available from: Official URL: http://jopr.mpob.gov.my/partition-coefficient-wate...

Abstract

The octanol/water partition coefficient (Pow) and water solubility (Sw) are important physico-chemical properties for an environmental risk assessment of a chemical substance as well as ecotoxicity. It can be an indication of the extent to which the chemical might bioaccumulate in aquatic organisms. The log Pow of palm-based fatty acids was estimated using high performance liquid chromatography (HPLC) method while the Sw value was determined using linear correlation between Sw and log Pow of reference compounds. The ecotoxicity of palm-based fatty acids was measured using test method OECD 203 Fish Acute Toxicity with common carp (Cyprinos carpio) as the test species. The short-chained C6 to C10 palm fatty acids were chosen for this study because they are generally toxic and can cause irritation to human and may have an adverse effect towards aquatic organisms. The log Pow values showed that both C6 and C8 fatty acids had low affinity towards aquatic organisms but C10 fatty acid showed medium affinity towards these organisms. As for water solubility C6 fatty acid had high affinity towards water while both C8 and C10 fatty acids showed medium affinity towards water. The LC50 value of C6 C8 and C10 palm FAs are 7 mg litre-1 7 mg litre-1 and 20 mg litre-1 respectively. It can be concluded that the higher the carbon chain number of the fatty acid the higher is the partition coefficient value the water solubility decreases. The palm-based fatty acid can be considered as moderately toxic to aquatic organisms. These data can be used by the palm-based oleochemical manufacturers for product registration preparation of product dossier or for marketing purposes.

[error in script]

Item Type:	Article
AGROVOC Term:	Palm oils
AGROVOC Term:	Fatty acids
AGROVOC Term:	Acute toxicity
AGROVOC Term:	Aquatic organisms
AGROVOC Term:	Common carp
AGROVOC Term:	Physicochemical properties
AGROVOC Term:	High performance liquid chromatography
AGROVOC Term:	Aquatic environment
AGROVOC Term:	Water
AGROVOC Term:	Solubility
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:28
URI:	http://webagris.upm.edu.my/id/eprint/24354

Actions (login required)

View Item