Optimisation of squalene recovery from palm oil by-product using integrated scco2 -pressure swing

Seyed Hamed Mirhosseini, . and Badlishah Sham Baharin, . and Mohd Helmi Ali, . and Norhidayah Suleiman, . and Md Zaidul Islam Sarker, . Optimisation of squalene recovery from palm oil by-product using integrated scco2 -pressure swing. pp. 570-578. ISSN 1511-2780

Squalene is used as an ingredient in functional foods pharmaceuticals and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of palm oil an effort has been made to find a potential source of squalene as an alternative to shark liver oil. The motivation for this work is to optimise its extraction from an alternative source a palm oil by-product known as palm fatty acid distillate (PFAD) using supercritical carbon dioxide (sc-CO2 ) with the aid of a pressure swing technique. The measurements were performed using a sc-CO2 extraction in a fixed bed at temperatures of 40C 50C and 60C pressures of 20 30 and 40 MPa and holding times of 20 30 and 40 min; high performance liquid chromatography (HPLC) was used for squalene content analysis optimised with a central composite design using research surface methodology (RSM). The second-order polynomial mathematical model adequately fitted the experimental results. The maximum squalene content from the model was predicted to be 356.24 ppm under the set of conditions with pressure of 23 MPa temperature at 40C and 20 min holding time.

Full text available from: Official URL: http://jopr.mpob.gov.my/optimisation-of-squalene-r...

Abstract

Squalene is used as an ingredient in functional foods pharmaceuticals and cosmetics. Due to the limitation of squalene availability from predominant source which is shark liver oil and to sustain the environment by fully utilising the by-product of palm oil an effort has been made to find a potential source of squalene as an alternative to shark liver oil. The motivation for this work is to optimise its extraction from an alternative source a palm oil by-product known as palm fatty acid distillate (PFAD) using supercritical carbon dioxide (sc-CO2 ) with the aid of a pressure swing technique. The measurements were performed using a sc-CO2 extraction in a fixed bed at temperatures of 40C 50C and 60C pressures of 20 30 and 40 MPa and holding times of 20 30 and 40 min; high performance liquid chromatography (HPLC) was used for squalene content analysis optimised with a central composite design using research surface methodology (RSM). The second-order polynomial mathematical model adequately fitted the experimental results. The maximum squalene content from the model was predicted to be 356.24 ppm under the set of conditions with pressure of 23 MPa temperature at 40C and 20 min holding time.

[error in script]

Item Type:	Article
AGROVOC Term:	Palm oils
AGROVOC Term:	Byproducts
AGROVOC Term:	Fatty acids
AGROVOC Term:	Extraction in chemical analysis
AGROVOC Term:	Supercritical CO2 extraction
AGROVOC Term:	Temperature
AGROVOC Term:	Pressure
AGROVOC Term:	HPLC
AGROVOC Term:	Optimization methods
AGROVOC Term:	Extraction
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:29
URI:	http://webagris.upm.edu.my/id/eprint/24988

Actions (login required)

View Item