Atypical chronic canine trypanosomosis: clinicoparasitological and hemato-biochemical appraisal


Citation

Singh C., . and Sharma A. K., . and Singh N. D., . and Singla L. D., . Atypical chronic canine trypanosomosis: clinicoparasitological and hemato-biochemical appraisal. pp. 54-59. ISSN 2180-3897

Abstract

This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.


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Abstract

This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.

Additional Metadata

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Item Type: Article
AGROVOC Term: Trypanosomiasis
AGROVOC Term: Trypanosoma
AGROVOC Term: Dogs
AGROVOC Term: Alanine aminotransferase
AGROVOC Term: Alkaline phosphatase
AGROVOC Term: Blood platelets
AGROVOC Term: Diagnosis
AGROVOC Term: Drug therapy
AGROVOC Term: Enzyme activity
AGROVOC Term: Haematology
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 24 Apr 2025 06:29
URI: http://webagris.upm.edu.my/id/eprint/25021

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