Atypical chronic canine trypanosomosis: clinicoparasitological and hemato-biochemical appraisal

Singh C., . and Sharma A. K., . and Singh N. D., . and Singla L. D., . Atypical chronic canine trypanosomosis: clinicoparasitological and hemato-biochemical appraisal. pp. 54-59. ISSN 2180-3897

This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.

Full text available from: Official URL: http://www.dvs.gov.my/dvs/resources/user_15/MJVR%2...

Abstract

This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.

[error in script]

Item Type:	Article
AGROVOC Term:	Trypanosomiasis
AGROVOC Term:	Trypanosoma
AGROVOC Term:	Dogs
AGROVOC Term:	Alanine aminotransferase
AGROVOC Term:	Alkaline phosphatase
AGROVOC Term:	Blood platelets
AGROVOC Term:	Diagnosis
AGROVOC Term:	Drug therapy
AGROVOC Term:	Enzyme activity
AGROVOC Term:	Haematology
Depositing User:	Ms. Suzila Mohamad Kasim
Last Modified:	24 Apr 2025 06:29
URI:	http://webagris.upm.edu.my/id/eprint/25021

Actions (login required)

View Item