Citation
Singh C., . and Sharma A. K., . and Singh N. D., . and Singla L. D., . Atypical chronic canine trypanosomosis: clinicoparasitological and hemato-biochemical appraisal. pp. 54-59. ISSN 2180-3897
Abstract
This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.
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Abstract
This report describes atypical chronic trypanosomosis in a three year male Spitz dog. Fever lethargy and anorexia were the early presenting signs without any hemato-biochemical abnormality. Peripheral blood smear examination was non-diagnostic on three consecutive times. Trypanosma evansi was confirmed in the Leishman stained thin blood smears (moderate parasetemia) on fourth parasitological examination. Biochemical profile showed a remarkable elevation in total serum bilirubin (6.7 mg) and activities of alanine amino transferase (ALT) (950 IU/L) and alkaline phosphatase (AKP) (1050 IU/L) after a month. Anemia leucopenia neutropenia lymphopenia and thrombocytopenia suggestive of bone marrow depression appeared by about 73 days of presentation of case. A rapid complete clinical recovery occurred within a week after treatment with quinapiramine sulphate and chloride combination 3.5mg/kg bwt. Hemoglobin leucocyte and thrombocyte count improved within six days however liver enzyme activity normalized slowly over three months.
Additional Metadata
Item Type: | Article |
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AGROVOC Term: | Trypanosomiasis |
AGROVOC Term: | Trypanosoma |
AGROVOC Term: | Dogs |
AGROVOC Term: | Alanine aminotransferase |
AGROVOC Term: | Alkaline phosphatase |
AGROVOC Term: | Blood platelets |
AGROVOC Term: | Diagnosis |
AGROVOC Term: | Drug therapy |
AGROVOC Term: | Enzyme activity |
AGROVOC Term: | Haematology |
Depositing User: | Ms. Suzila Mohamad Kasim |
Last Modified: | 24 Apr 2025 06:29 |
URI: | http://webagris.upm.edu.my/id/eprint/25021 |
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