Citation
Riyadi P.H., . and Tanod W.A., . and Dewanto D.K., . and Herawati V.E., . and Susanto E., . and Aisiah S., . (2021) Chemical profiles and antioxidant properties of Bruguiera gymnorrhiza fruit extracts from Central Sulawesi, Indonesia. Food Research (Malaysia), 5 (S3). pp. 37-47. ISSN 2550-2166
Abstract
Bruguiera gymnorrhiza is one of the mangrove species that a source of antioxidants. Antioxidant substances are able to protect cells from oxidative stress and other related diseases. This study aimed to evaluate the chemical profiles, predicted biological activity, and antioxidant activity of the B. gymnoriza fruit extracts. The research methods included sampling, extraction (maceration with MeOH:DCM), identification of chemical profiles (GCMS spectra analysis), assaying for computational analysis (PASS server and ADMET), antioxidants (DPPH radical scavenging), and total phenolic content (Folin-Ciocalteu). Bruguiera gymnorrhiza fruits was collected from Central Sulawesi, Indonesia. The chemical profiles detected in the B. gymnorrhiza fruit extracts, namely isopimaradiene (64.20%); 4-(2-Aminopropyl) phenol (19.06%); dimethylamino- dimethylphosphene oxide (9.40%); 3-amino-2-benzylbutanoic acid (5.46%); and 1,4-dideuteriooctane (1.89%). PASS server analysis showed that the five compounds detected from B. gymnorrhiza fruit have the potential as an NF-E2-related factor (Nrf2) stimulant and oxygen scavenger. The ADMET analysis results indicated that B. gymnorrhiza fruits could be developed as folk medicine and nutraceutical products.
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Abstract
Bruguiera gymnorrhiza is one of the mangrove species that a source of antioxidants. Antioxidant substances are able to protect cells from oxidative stress and other related diseases. This study aimed to evaluate the chemical profiles, predicted biological activity, and antioxidant activity of the B. gymnoriza fruit extracts. The research methods included sampling, extraction (maceration with MeOH:DCM), identification of chemical profiles (GCMS spectra analysis), assaying for computational analysis (PASS server and ADMET), antioxidants (DPPH radical scavenging), and total phenolic content (Folin-Ciocalteu). Bruguiera gymnorrhiza fruits was collected from Central Sulawesi, Indonesia. The chemical profiles detected in the B. gymnorrhiza fruit extracts, namely isopimaradiene (64.20%); 4-(2-Aminopropyl) phenol (19.06%); dimethylamino- dimethylphosphene oxide (9.40%); 3-amino-2-benzylbutanoic acid (5.46%); and 1,4-dideuteriooctane (1.89%). PASS server analysis showed that the five compounds detected from B. gymnorrhiza fruit have the potential as an NF-E2-related factor (Nrf2) stimulant and oxygen scavenger. The ADMET analysis results indicated that B. gymnorrhiza fruits could be developed as folk medicine and nutraceutical products.
Additional Metadata
| Item Type: | Article |
|---|---|
| Additional Information: | The 6th International Conference on Tropical and Coastal Region Eco-Development (ICTCRED) 2020 |
| AGROVOC Term: | mangroves |
| AGROVOC Term: | fruit extracts |
| AGROVOC Term: | extraction |
| AGROVOC Term: | chemical analysis |
| AGROVOC Term: | gas chromatography |
| AGROVOC Term: | medicinal plants |
| AGROVOC Term: | Antioxidants |
| AGROVOC Term: | phenolic compounds |
| Geographical Term: | Indonesia |
| Depositing User: | Mr. Khoirul Asrimi Md Nor |
| Date Deposited: | 28 Jan 2026 07:03 |
| Last Modified: | 28 Jan 2026 07:03 |
| URI: | http://webagris.upm.edu.my/id/eprint/3300 |
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