The effect of high protein milk supplementation on satiety in normal weight subjects

Muliadi, R.D. and Kartawidjajaputra, F. and Antono, L. (2022) The effect of high protein milk supplementation on satiety in normal weight subjects. Food Research (Malaysia), 6. pp. 96-102. ISSN 2550-2166

Obesity has become a serious problem in the world. Protein is known for giving higher satiety rather than other macronutrients. However, most studies conducted their research on, either overweight or obese subjects, whereas the satiety response might be different. The objective of the study was to evaluate the effect of high protein milk (HPM) supplementation on self-reported satiety and energy intake in healthy adult men with normal BMI (18.5 – 22.9 kg/m²). In a controlled single-blind cross-over study, 17 healthy adult men (age 27±5 years; BMI 21.4±1.13 kg/m²) attended 2 sessions 1 week apart. In each session, all participants consumed a drink of 200 mL HPM (12 g protein, 2.5 g fat, 12 g carbohydrate, 120 kcal) or standard protein milk (SPM) (4g protein, 2.5 g fat, 20 g carbohydrate, 120 kcal) together with standardized breakfast±4 hours before ad libitum lunch. The result showed that fullness and hunger ratings were significantly greater on HPM supplementation than SPM (P = 0.031, P = 0.043, respectively). However, there was no significant effect on the rating of the desire to eat (P = 0.123) and energy intake during lunch (P = 0.926). The results support the hypothesis that supplementation of HPM could improve satiety in healthy adult men with normal BMI.

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Abstract

Obesity has become a serious problem in the world. Protein is known for giving higher satiety rather than other macronutrients. However, most studies conducted their research on, either overweight or obese subjects, whereas the satiety response might be different. The objective of the study was to evaluate the effect of high protein milk (HPM) supplementation on self-reported satiety and energy intake in healthy adult men with normal BMI (18.5 – 22.9 kg/m²). In a controlled single-blind cross-over study, 17 healthy adult men (age 27±5 years; BMI 21.4±1.13 kg/m²) attended 2 sessions 1 week apart. In each session, all participants consumed a drink of 200 mL HPM (12 g protein, 2.5 g fat, 12 g carbohydrate, 120 kcal) or standard protein milk (SPM) (4g protein, 2.5 g fat, 20 g carbohydrate, 120 kcal) together with standardized breakfast±4 hours before ad libitum lunch. The result showed that fullness and hunger ratings were significantly greater on HPM supplementation than SPM (P = 0.031, P = 0.043, respectively). However, there was no significant effect on the rating of the desire to eat (P = 0.123) and energy intake during lunch (P = 0.926). The results support the hypothesis that supplementation of HPM could improve satiety in healthy adult men with normal BMI.

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Item Type:	Article
AGROVOC Term:	milk
AGROVOC Term:	proteins
AGROVOC Term:	macronutrients
AGROVOC Term:	food supplementation
AGROVOC Term:	men
AGROVOC Term:	satiety
AGROVOC Term:	hunger
AGROVOC Term:	obesity
Geographical Term:	Indonesia
Depositing User:	Mr. Khoirul Asrimi Md Nor
Date Deposited:	20 Feb 2026 08:09
Last Modified:	20 Feb 2026 08:09
URI:	http://webagris.upm.edu.my/id/eprint/3466

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