Screening of high astragalin compound in selected Moringa oleifera genotypes for future breeding programme

Farah Fazwa Md. Ariff, . and Sures Kumar Muniandi, . and Syafiqah Nabilah Samsul Bahari, . and Norhayati Saffie, . and Fara Shazwanie Omar Tarmizi, . and Zunoliza Abdullah, . and Ling, Sui Kiong and Mohd Zaki Abdullah, . (2022) Screening of high astragalin compound in selected Moringa oleifera genotypes for future breeding programme. International Journal of Agriculture, Forestry and Plantation (Malaysia), 12. pp. 91-96. ISSN 2462-1757

Moringa oleifera L. or locally known as merunggai is a valuable multipurpose tree species widely planted for their edible vegetative parts enriched with health benefitting nutrients. It has been used for centuries due to its high medicinal value having antifungal, antiviral, antidepressant, and anti-inflammatory properties. Isoquercetin, astragalin, and crypto-chlorogenic acid are the major bioactive compounds found in M. oleifera leaves. Astragalin or also known as 3-O-glucoside of kaempferol is a major flavonoid isolated from M.oleifera leaves and acts as a natural antioxidant agent exhibiting biological activities such as antioxidant, anti-inflammation, anti-obesity, anti-diabetic, anti-cancer, neuroprotective. It also exhibits some wound healing properties and inhibition of dermatitis and other skin diseases. Due to the numerous pharmacological benefits of M. oleifera, thus a study was conducted to select high-yielding genotypes of M. oleifera based on one of the important bioactive compounds, astragalin. Selection of mother plants was carried out at three different populations in Peninsular Malaysia such as Seberang Perai (Penang), Port Dickson, (Negeri Sembilan), and Tangkak (Johor). A total of 30 mother trees labelled with different code number from each site were selected based on their superior morphological traits and health condition. Screening on high-yielding clones with high astragalin content was conducted through High-Performance Liquid Chromatography (HPLC) analysis of moringa leaves extract. This paper highlights the process of sample collection from various sites and screening work of superior genotypes. As an output, several genotypes of M. oleifera having superior phenotypic characteristics and bioactive compounds have been identified. Through screening and individual selection, plant genotypes with wide variation and genetic backgrounds can be improved for the development of new clones or varieties. Outputs from the study are not only beneficial to the plant breeder in the aspect of producing new varieties but also to herbal industries in producing high-quality herbal products.

Full text available from: Official URL: https://ijafp.org/wp-content/uploads/2022/09/IJAFP...

Abstract

Moringa oleifera L. or locally known as merunggai is a valuable multipurpose tree species widely planted for their edible vegetative parts enriched with health benefitting nutrients. It has been used for centuries due to its high medicinal value having antifungal, antiviral, antidepressant, and anti-inflammatory properties. Isoquercetin, astragalin, and crypto-chlorogenic acid are the major bioactive compounds found in M. oleifera leaves. Astragalin or also known as 3-O-glucoside of kaempferol is a major flavonoid isolated from M.oleifera leaves and acts as a natural antioxidant agent exhibiting biological activities such as antioxidant, anti-inflammation, anti-obesity, anti-diabetic, anti-cancer, neuroprotective. It also exhibits some wound healing properties and inhibition of dermatitis and other skin diseases. Due to the numerous pharmacological benefits of M. oleifera, thus a study was conducted to select high-yielding genotypes of M. oleifera based on one of the important bioactive compounds, astragalin. Selection of mother plants was carried out at three different populations in Peninsular Malaysia such as Seberang Perai (Penang), Port Dickson, (Negeri Sembilan), and Tangkak (Johor). A total of 30 mother trees labelled with different code number from each site were selected based on their superior morphological traits and health condition. Screening on high-yielding clones with high astragalin content was conducted through High-Performance Liquid Chromatography (HPLC) analysis of moringa leaves extract. This paper highlights the process of sample collection from various sites and screening work of superior genotypes. As an output, several genotypes of M. oleifera having superior phenotypic characteristics and bioactive compounds have been identified. Through screening and individual selection, plant genotypes with wide variation and genetic backgrounds can be improved for the development of new clones or varieties. Outputs from the study are not only beneficial to the plant breeder in the aspect of producing new varieties but also to herbal industries in producing high-quality herbal products.

[error in script]

Item Type:	Article
AGROVOC Term:	Moringa oleifera
AGROVOC Term:	flavonoids
AGROVOC Term:	antioxidants
AGROVOC Term:	nutrients
AGROVOC Term:	screening
AGROVOC Term:	breeding programmes
AGROVOC Term:	chemical analysis
AGROVOC Term:	selection
AGROVOC Term:	genotypes
Geographical Term:	Malaysia
Depositing User:	Mr. Khoirul Asrimi Md Nor
Date Deposited:	20 May 2026 06:31
Last Modified:	20 May 2026 06:31
URI:	http://webagris.upm.edu.my/id/eprint/3907

Actions (login required)

View Item