Maternal vitamin D intake and serum 25-hydroxyvitamin D (25(OH)D) levels associated with blood pressure: a cross-sectional study in Padang West Sumatra

Faradila Faradila, . and Aji Arif Sabta, . and Sukma Nazla Putri, . and Lipoeto Nur Indrawaty, . and Ayudia Fanny, . Maternal vitamin D intake and serum 25-hydroxyvitamin D (25(OH)D) levels associated with blood pressure: a cross-sectional study in Padang West Sumatra. pp. 407-415. ISSN 1394-035X

The association between vitamin D inadequacy and blood pressure (BP) has been studied in several populations. We examined the association of maternal vitamin D intake and serum 25(OH)D levels and BP among pregnant women in West Sumatra. Methods: This study was conducted using a comparative cross-sectional study in a maternal clinic selected by convenience in Padang. Pregnant mothers who attended the clinic in July-August 2015 were recruited. Inclusion criteria were pregnancy between 28-42 weeks aged 20-35 years and with less than three parity status. A total of 56 women were recruited and divided equally into either normotension or hypertension groups. Subjects with blood pressure less than 120 mmHg (SBP) and 80 mmHg (DBP) were placed in the normotension group while subjects with 140 mmHg (SBP) and/or 90 mmHg) were in the hypertension group. Subjects completed a pre-tested semi-quantitative food frequency questionnaire. Three ml of non-fasting blood was drawn from each subject for determination of 25(OH)D urea creatinine leukocyte and blood glucose levels. Results: There was a significant difference in mean serum 25(OH)D between the normotension and hypertension groups at 36.8521.58 pg/ml and 17.367.91 pg/ml respectively. Only 20 of participants from the hypertension group had adequate vitamin D intake. Blood pressure status had a significant association with vitamin D intake status (p0.001). Conclusion: Maternal vitamin D intake and 25(OH)D levels were associated with blood pressure status in this sample population. Further studies with a larger sample population are suggested to verify the findings of this study.

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Abstract

The association between vitamin D inadequacy and blood pressure (BP) has been studied in several populations. We examined the association of maternal vitamin D intake and serum 25(OH)D levels and BP among pregnant women in West Sumatra. Methods: This study was conducted using a comparative cross-sectional study in a maternal clinic selected by convenience in Padang. Pregnant mothers who attended the clinic in July-August 2015 were recruited. Inclusion criteria were pregnancy between 28-42 weeks aged 20-35 years and with less than three parity status. A total of 56 women were recruited and divided equally into either normotension or hypertension groups. Subjects with blood pressure less than 120 mmHg (SBP) and 80 mmHg (DBP) were placed in the normotension group while subjects with 140 mmHg (SBP) and/or 90 mmHg) were in the hypertension group. Subjects completed a pre-tested semi-quantitative food frequency questionnaire. Three ml of non-fasting blood was drawn from each subject for determination of 25(OH)D urea creatinine leukocyte and blood glucose levels. Results: There was a significant difference in mean serum 25(OH)D between the normotension and hypertension groups at 36.8521.58 pg/ml and 17.367.91 pg/ml respectively. Only 20 of participants from the hypertension group had adequate vitamin D intake. Blood pressure status had a significant association with vitamin D intake status (p0.001). Conclusion: Maternal vitamin D intake and 25(OH)D levels were associated with blood pressure status in this sample population. Further studies with a larger sample population are suggested to verify the findings of this study.

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Item Type:	Article
AGROVOC Term:	Blood pressure
AGROVOC Term:	Hypertension
AGROVOC Term:	Pregnancy
AGROVOC Term:	Nutrient intake
AGROVOC Term:	Blood sugar
AGROVOC Term:	Nutrition
AGROVOC Term:	Centrifuging
AGROVOC Term:	Optical density
AGROVOC Term:	Enzyme linked immunosorbent assay
AGROVOC Term:	Questionnaires
Depositing User:	Mr. AFANDI ABDUL MALEK
Last Modified:	24 Apr 2025 00:54
URI:	http://webagris.upm.edu.my/id/eprint/7998

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