Overview of the pharmacological activities of Aframomum melegueta

Soi Moi Chye, . and Chooi Ling Lim, . and Rhun Yian Koh, . and Yu Edwin Sheng Toh, . and Pick Anna Kiong Ling, . Overview of the pharmacological activities of Aframomum melegueta. pp. 1-13. ISSN 1511-3701

Aframomum melegueta (AM) is an herbaceous plant consumed as an edible spice and traditionally used to treat common ailments in West Africa such as body pains diarrhoea sore throat catarrh congestion and rheumatism. Moreover AM has been used to treat infectious diseases such as urinary tract infections caused by Escherichia coli Klebsiella pneumoniae Enterococcus faecalis Staphylococcus saprophyticus Proteus mirabilis methicillin-resistant Staphylococcus aureus Salmonella spp and Shigella spp. Based on current literature different parts of the plant possess specific phytochemicals such as flavonoids phenolic compounds alkaloids tannins terpenoids saponins and cardiac glycosides that have healing potential and medicinal purposes. These phytochemicals exhibit anti-inflammatory antimicrobial anti-allergic anti-clotting anti-cancer antidiabetic and hepatoprotective effects. They also act as antioxidants to counteract free radicals and immune enhancers as well as hormone modulators. However research on medicinal properties of AM is still very limited. Therefore more comprehensive studies need to be performed to elucidate the medicinal purposes of AM. This review summarises findings from previous studies on the pharmacological activities of AM.

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Abstract

Aframomum melegueta (AM) is an herbaceous plant consumed as an edible spice and traditionally used to treat common ailments in West Africa such as body pains diarrhoea sore throat catarrh congestion and rheumatism. Moreover AM has been used to treat infectious diseases such as urinary tract infections caused by Escherichia coli Klebsiella pneumoniae Enterococcus faecalis Staphylococcus saprophyticus Proteus mirabilis methicillin-resistant Staphylococcus aureus Salmonella spp and Shigella spp. Based on current literature different parts of the plant possess specific phytochemicals such as flavonoids phenolic compounds alkaloids tannins terpenoids saponins and cardiac glycosides that have healing potential and medicinal purposes. These phytochemicals exhibit anti-inflammatory antimicrobial anti-allergic anti-clotting anti-cancer antidiabetic and hepatoprotective effects. They also act as antioxidants to counteract free radicals and immune enhancers as well as hormone modulators. However research on medicinal properties of AM is still very limited. Therefore more comprehensive studies need to be performed to elucidate the medicinal purposes of AM. This review summarises findings from previous studies on the pharmacological activities of AM.

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Item Type:	Article
AGROVOC Term:	Aframomum melegueta
AGROVOC Term:	Herbaceous plants
AGROVOC Term:	Pharmacology
AGROVOC Term:	Phytochemistry
AGROVOC Term:	Medicinal properties
AGROVOC Term:	Therapeutic substances
AGROVOC Term:	Diarrhoea
AGROVOC Term:	Rheumatism
AGROVOC Term:	Infectious diseases
AGROVOC Term:	Urinary tract diseases
Depositing User:	Mr. AFANDI ABDUL MALEK
Last Modified:	24 Apr 2025 00:54
URI:	http://webagris.upm.edu.my/id/eprint/8119

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