Citation
Ansar S., . and Alkhudhayr B. M. A., . and Alsubki R., . and Tabassum H., . and Ali M. N., . and Alnajran H. A., . and Abudawood M., . Synthesis of biogenic silver nanoparticles from polyphenolic Brassica nigra and their potential antifungal antibacterial antioxidant and anticancer activities. pp. 317-325. ISSN 22317546
Abstract
Green synthesis of silver nanoparticles (AgNPs) has consistently revolutionised the field of nanotechnology and bio-based AgNPs have emerged as efficient therapeutic tools in biomedical science. Synthesis and characterization of silver nanoparticles from Brassica nigra (BN) and evaluation of antifungal anticancer antibacterial and antioxidant activities were investigated in this study. The characteristics of BN-AgNPs was studied using various spectroscopic techniques measuring ultraviolet-visible (UV“Vis) spectra determination of particle size zeta potential scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Elemental composition was determined using energy-dispersive spectroscopy (EDX). Formation of AgNPs was confirmed by UV“Vis spectroscopy. Cytotoxic activity was determined at different nanoparticle concentrations on the MCF-7 cell line with the maximum cytotoxic effect observed at 100 g/ml. BN-AgNPs also showed strong antifungal and antimicrobial activities along with antioxidant properties. The green synthesis of nanoparticles is comparatively simple eco-friendly and safer than conventional methods and the observed anticancer activity in the current report is suggestive of the biogenic AgNPs as therapeutic agent for cancer therapy.
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Abstract
Green synthesis of silver nanoparticles (AgNPs) has consistently revolutionised the field of nanotechnology and bio-based AgNPs have emerged as efficient therapeutic tools in biomedical science. Synthesis and characterization of silver nanoparticles from Brassica nigra (BN) and evaluation of antifungal anticancer antibacterial and antioxidant activities were investigated in this study. The characteristics of BN-AgNPs was studied using various spectroscopic techniques measuring ultraviolet-visible (UV“Vis) spectra determination of particle size zeta potential scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Elemental composition was determined using energy-dispersive spectroscopy (EDX). Formation of AgNPs was confirmed by UV“Vis spectroscopy. Cytotoxic activity was determined at different nanoparticle concentrations on the MCF-7 cell line with the maximum cytotoxic effect observed at 100 g/ml. BN-AgNPs also showed strong antifungal and antimicrobial activities along with antioxidant properties. The green synthesis of nanoparticles is comparatively simple eco-friendly and safer than conventional methods and the observed anticancer activity in the current report is suggestive of the biogenic AgNPs as therapeutic agent for cancer therapy.
Additional Metadata
Item Type: | Article |
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AGROVOC Term: | Brassica nigra |
AGROVOC Term: | Antifungal agents |
AGROVOC Term: | Antibacterial agents |
AGROVOC Term: | Statistical analysis |
AGROVOC Term: | Antioxidants |
AGROVOC Term: | Cancer (disease) |
AGROVOC Term: | Plant extracts |
Depositing User: | Mr. AFANDI ABDUL MALEK |
Last Modified: | 24 Apr 2025 00:55 |
URI: | http://webagris.upm.edu.my/id/eprint/9872 |
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