In vitro anti-inflammatory activity of selected medicinal plants from the family annonaceae


Citation

Mazura M P., . and Nor Azah M A., . and Saidatul Husni S., . and Nik Yasmin N Y., . and Mailina J., . and Mohammad Faridz Z P., . and Siti Humeirah A G., . and Ahmad Abdul Qayyum M., . (2009) In vitro anti-inflammatory activity of selected medicinal plants from the family annonaceae. [Proceedings Paper]

Abstract

A total of six methanolic extracts of leaves from selected Annonaceae species namely Xylopia elliptica X. malayana Polyalthia rumphii Pseuduvaria macrophylla Cyathocalyx ramulijlorus and Goniothalamus macrophyllus were extracted using solvent extraction technique. All the samples were investigated for their anti-inflammatory effect by using hyaluronidase lipoxygenase and xanthine oxidase inhibitory assay. From the results obtained the extract of Polyalthia rumphii showed the highest inhibitory effect in hyaluronidase inhibitory assay with 100 inhibition which was followed by the extract of X. elliptica 85.7 and the extract of C. ramuliflorus 62.2 respectively. For xanthine oxidase and lipoxygenase assay all the extracts gave low activity except X malayana with moderate activity 74.2 in xanthine oxidase assay. No activity was showed by the extract of Pseuduvaria macrophylla in hyaluronidase and xanthine oxidase inhibitory assays.


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Abstract

A total of six methanolic extracts of leaves from selected Annonaceae species namely Xylopia elliptica X. malayana Polyalthia rumphii Pseuduvaria macrophylla Cyathocalyx ramulijlorus and Goniothalamus macrophyllus were extracted using solvent extraction technique. All the samples were investigated for their anti-inflammatory effect by using hyaluronidase lipoxygenase and xanthine oxidase inhibitory assay. From the results obtained the extract of Polyalthia rumphii showed the highest inhibitory effect in hyaluronidase inhibitory assay with 100 inhibition which was followed by the extract of X. elliptica 85.7 and the extract of C. ramuliflorus 62.2 respectively. For xanthine oxidase and lipoxygenase assay all the extracts gave low activity except X malayana with moderate activity 74.2 in xanthine oxidase assay. No activity was showed by the extract of Pseuduvaria macrophylla in hyaluronidase and xanthine oxidase inhibitory assays.

Additional Metadata

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Item Type: Proceedings Paper
Additional Information: Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. mal QK99 M3S471 2008 Call Number
AGROVOC Term: DRUG PLANTS
AGROVOC Term: ANNONACEAE
AGROVOC Term: IN VITRO
AGROVOC Term: INFLAMMATION
AGROVOC Term: MALAYSIA
Geographical Term: MALAYSIA
Depositing User: Ms. Suzila Mohamad Kasim
Last Modified: 24 Apr 2025 05:14
URI: http://webagris.upm.edu.my/id/eprint/11362

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