Citation
Khozirah S., . and Nordin H. L., . and Suryati Y., . and Umi Kalsom Y., . and Faridah A., . and Zurina Z., . and Israf D. A., . (2004) HPLC-DAD-ESI-MS/MS profiling of the no inhibitory fractions of Melicope ptelefolia. [Proceedings Paper]
Abstract
Dereplication of the NO inhibitory fractions of the Melicope ptelefolia using high performance liquid chromatography HPLC-diode array detector DAD-mass spectrometry MS has identified seven main constituents. The compounds were identified as kokusaginine 1 compound 2 possibly kokusagine 2a or 5methoxymaculine 2b 2 4 6-trihydroxy-3-prenylacetophenone 3 2 4 6 trihydroxy-3-geranylacetophenone 4 2 4 6-trihydroxy-3geranylgeranylacetophenone 5 3-4-0-3 7-dimethyl-2 6-octadienylphenyl-2-propenoic acid 6 and 2 4 6-trihydroxy-3-farnesylgeranylacetophenone 7. While the identity of 1 4 and 6 were unequivocally confirmed by isolation and spectroscopic evidences the identification of the other compounds are tentative based on their MS and MS/MS data. Compound 4 is a new natural product while compounds 5 and 7 are tentatively new.
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Abstract
Dereplication of the NO inhibitory fractions of the Melicope ptelefolia using high performance liquid chromatography HPLC-diode array detector DAD-mass spectrometry MS has identified seven main constituents. The compounds were identified as kokusaginine 1 compound 2 possibly kokusagine 2a or 5methoxymaculine 2b 2 4 6-trihydroxy-3-prenylacetophenone 3 2 4 6 trihydroxy-3-geranylacetophenone 4 2 4 6-trihydroxy-3geranylgeranylacetophenone 5 3-4-0-3 7-dimethyl-2 6-octadienylphenyl-2-propenoic acid 6 and 2 4 6-trihydroxy-3-farnesylgeranylacetophenone 7. While the identity of 1 4 and 6 were unequivocally confirmed by isolation and spectroscopic evidences the identification of the other compounds are tentative based on their MS and MS/MS data. Compound 4 is a new natural product while compounds 5 and 7 are tentatively new.
Additional Metadata
| Item Type: | Proceedings Paper |
|---|---|
| Additional Information: | Available at Perpustakaan Sultan Abdul Samad Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia. QK710.2 M239 2004 Call Number |
| AGROVOC Term: | Rutaceae |
| AGROVOC Term: | Leaves |
| AGROVOC Term: | Air drying |
| AGROVOC Term: | Leaf extracts |
| AGROVOC Term: | High performance liquid chromatography |
| AGROVOC Term: | Mass spectrometry |
| AGROVOC Term: | Fractionation |
| AGROVOC Term: | Butanol |
| AGROVOC Term: | Isolation in chemical analysis |
| AGROVOC Term: | Plant extracts |
| Geographical Term: | MALAYSIA |
| Depositing User: | Ms. Suzila Mohamad Kasim |
| Last Modified: | 24 Apr 2025 05:15 |
| URI: | http://webagris.upm.edu.my/id/eprint/12811 |
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